Jobs · Connecticut

Vice President, Asset Team Leader

Arvinas · New Haven, CT · 2 wk ago
Full-time

Arvinas is a biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins. Arvinas uses its proprietary PROTAC Discovery Engine platform to engineer PROteolysis TArgeting Chimeras, or PROTACs, designed to harness the body’s own natural protein disposal system to selectively and efficiently degrade and remove disease-causing proteins. This approach has enabled Arvinas to build a broad pipeline of investigational therapies across oncology and neurodegenerative diseases, including:

  • ARV-102, targeting LRRK2 for neurodegenerative diseases
  • ARV-806, targeting KRAS G12D for mutated cancers, including pancreatic, colorectal, and non-small cell lung cancers
  • ARV-393, targeting BCL6 for relapsed/refractory non-Hodgkin Lymphoma
  • ARV-027, targeting polyglutamine-expanded androgen receptor (polyQ-AR) in skeletal muscle for spinal bulbar muscular atrophy
  • Vepdegestrant, targeting the estrogen receptor for patients with locally advanced or metastatic ER+/HER2- breast cancer

In May 2026, Arvinas achieved a major milestone with the first-ever U.S. Food and Drug Administration (FDA) approval of a PROTAC protein degrader therapy, demonstrating the therapeutic potential of targeted protein degradation. #TeamArvinas values diverse thoughts and perspectives, fostering an environment where employees pursue innovation, think creatively, and contribute to the company’s mission of improving patient lives.

About the role

Arvinas is seeking a highly experienced Development Asset Team Leader to apply expert-level knowledge of biology and drug development mechanisms to lead cross-functional teams responsible for the scientific strategy and execution of early oncology development programs. This role reports to the SVP, Asset Strategy and Team Leadership and can be remote, hybrid, or based at the New Haven, CT headquarters.

Responsibilities

  • Apply up-to-date knowledge of biology, disease mechanisms, and drug development to lead strategy creation, achieve development milestones, and maximize asset value.
  • Lead the development of long-range objectives and strategies as part of the Integrated Development Plan with a multidisciplinary team.
  • Align plans with governance and executive management, and communicate with senior leaders, peers, and functional representatives.
  • Collaborate with functional leads to create and evaluate scenario plans based on external landscape and business needs; negotiate with and influence key stakeholders.
  • Process and interpret biological and scientific data to continually reassess drug development strategy and operational plans.
  • Lead the External Engagement subteam to ensure assets are represented externally in alignment with corporate and asset strategies, including publication planning, KOL engagement, and partnerships.
  • Represent Arvinas at conferences and technical engagements.
  • Use scientific expertise to guide team decisions, solve strategic and operational problems, and coordinate activities across Clinical Research, Clinical Operations, Regulatory, CMC, New Product Planning, and Project Management.
  • Analyze biological, preclinical, and clinical data to identify trends and solve problems; detect changes impacting plans.
  • Collaborate with Project Managers on program progress, cost, resource allocation, timelines, and risk management.
  • Estimate time, costs, and resources for work activities; monitor and control resources.
  • Evaluate scientific and biological information for compliance with standards; review reports and proposals for accuracy and adherence to policies and regulations.
  • Lead cross-functional oncology asset teams and act as the main point of contact for executive management.
  • Interpret biological and scientific data for senior leaders and external stakeholders.
  • Work with Business Development and Alliance Management on partnership opportunities and partnered programs.
  • Represent programs at governance and decision-making meetings.
  • Support corporate objectives, including Board meeting preparation, earnings preparations, and corporate presentations.
  • Drive team objective setting, prioritization, and performance to ensure adherence to plans and strategies.
  • Coach and develop others, providing consultation and advice based on drug development and scientific experience.
  • Foster a positive team environment through trust, transparent communication, and consensus-building.
  • Organize, plan, and prioritize team work to align with goals and endorsed plans.
  • Partner with Research to provide scientific and drug development expertise as programs advance from exploratory research into development.

Requirements

  • Advanced education in biology or a closely related scientific field.
  • Significant oncology drug development and scientific leadership experience in the biotechnology/pharmaceutical industry.
  • Leadership experience across all phases of drug development in oncology, grounded in a strong foundation in biology.
  • Minimum of 15 years of relevant industry experience, with at least 5 years in a scientific leadership role leading cross-functional drug development asset teams.
  • Leadership experience must be specific to asset development teams, not limited to functional or subteam leadership.
  • Experience in more than one drug development discipline; hematology oncology preferred.
  • Proven ability to apply biological expertise and scientific rigor to data interpretation, strategy planning, and implementation.
  • Proactive and strategic thinker with strong decision-making skills.
  • Ability to function effectively across a matrix organization with multiple stakeholders.
  • Demonstrated experience leading teams effectively, efficiently, and on target.
  • Strong interpersonal and communication skills, including presentation skills, with success influencing all levels cross-functionally.
  • Excellent business acumen and judgment, with the ability to align teams to corporate strategy.
  • Highly collaborative with outstanding relationship-building skills.

Qualifications

  • Bachelor’s degree in biology or a closely related life science field (e.g., Microbiology, Chemistry, Clinical Research, or Health Science) required, with a minimum of 15 years of relevant industry experience, including at least 5 years in a scientific leadership role; or equivalent combination of education and experience.
  • Specific training in an area of drug development, such as Clinical Research, required.
  • Held senior-level roles in the pharmaceutical industry with engagement at the executive leadership or board level.

Benefits

Arvinas offers a competitive package of base and incentive compensation, as well as a comprehensive benefits program designed to support the health, wellness, and financial security of employees and their families. Benefits include group medical, vision, and dental coverage, group and supplemental life insurance, and more.

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