Translational Medicine Associate Director

About the role

As a Translational Science Associate Director, you will be responsible for implementing translational and biomarker objectives for cellular, biologics, and small molecule therapies for immune-mediated diseases. Your focus will be on ensuring effective collaborations between research and development, establishing strong target-to-disease connections, differentiating AZ therapeutics, and driving translational understanding of clinical trial data.

Responsibilities

• Oversee translational study strategy and deliverables with CROs and collaborators to support new and ongoing clinical studies as well as to enable our life cycle management strategy and new program strategies as a global product team level translational lead.
• Recognized as an authority in translational science and work on complex therapeutic projects and scientific problems, providing solutions that are highly innovative.

Requirements

• PhD or MD-PhD degree in a relevant field required. Degree or training in Immunology preferred.
• 3 or more years of industry or 5 yrs combined academic/industry experience in clinical development or translational science.
• Strong knowledge of the pathogenesis of immune mediated disease and the application of cellular, molecular technologies and models to drive program decisions.
• Prior experience in clinical biomarker strategy development and execution including human target validation, target engagement, and molecular differentiation.
• Significant experience managing CROs for translational studies and biomarkers for clinical trials.
• Detailed understanding of translational and clinical research methodology and biostatistics principles.
• Attention to detail, strive to generate high-quality work, and sense of passion and urgency to achieve team and program goals.
• Demonstrated experience contributing to and leading complex projects.
• Demonstrated track record in delivering results.
• Outstanding verbal and written communication skills.
• Excellent analytical, problem solving and strategic planning skills.

Qualifications

• Experience in clinical biomarker development of T-cell therapy and/or other advanced therapeutic modalities in house or with CROs.
• Experience in the authoring of relevant sections of regulatory documents.
• Understanding of the full drug development process, with experience across phases of therapeutic development and studies.
• Understanding of FDA, EMA, MHRA and ICH GCP guidelines as they pertain to translational strategy.

Skills

• Experience in the authoring of relevant sections of regulatory documents.
• Understanding of the full drug development process, with experience across phases of therapeutic development and studies.
• Understanding of FDA, EMA, MHRA and ICH GCP guidelines as they pertain to translational strategy.

Benefits

• Qualified retirement programs.
• Paid time off (i.e., vacation, holiday, and leaves).
• Health, dental, and vision coverage.

Pay

The annual base pay (or hourly rate of compensation) for this position ranges from $135,558.40 - 202,587.60 USD Annual.

Schedule

Not specified.