Technical Development Operations Specialist

About the role

Cabaletta Bio (Nasdaq: CABA) is a late-stage clinical biotechnology company focused on developing and launching curative targeted cell therapies designed specifically for patients with autoimmune diseases. The CABA™ platform encompasses two complementary strategies which aim to advance the discovery and development of engineered T cell therapies with the potential to become deep and durable, perhaps curative, treatments for a broad range of autoimmune diseases. The lead CARTA (Chimeric Antigen Receptor T cells for Autoimmunity) strategy is prioritizing the development of rese-cel, a 4-1BB-containing fully human CD19-CAR T cell investigational therapy. Rese-cel is currently being evaluated in the RESET™ (REstoring SElf-Tolerance) clinical development program spanning multiple therapeutic areas, including rheumatology, neurology and dermatology. Cabaletta Bio's headquarters and labs are located in Philadelphia, PA. Location: On‑Site/Philadelphia, PA.

Responsibilities

• Coordinate and maintain laboratory scheduling across Technical Development teams, including shared laboratory spaces, equipment, and other constrained resources
• Partner with scientific teams to translate development plans and project priorities into executable laboratory schedules
• Maintain inventory management processes for laboratory consumables, raw materials, and other development supplies
• Partner with scientists to forecast material requirements and coordinate replenishment to ensure materials are available to support planned laboratory activities
• Partner with scientists and cross-functional stakeholders to anticipate operational needs and help resolve scheduling, material, or resource conflicts.
• Serve as liaison between the Technical Development organization and the Lab Operations team to enable effective partnership
• Identify and escalate lab-related bottlenecks (e.g., lab space issues, equipment availability, etc.)
• Support training of new team members on Technical Development operations
• Identify opportunities to reduce material waste, expired inventory, redundant purchases and unnecessary costs
• Coordinate shipment of time-sensitive materials and samples
• Coordinate receipt, reconciliation, storage and distribution of incoming materials and samples
• Track equipment status and proactively communicate downtime or capacity constraints to laboratory teams
• Support the development and maintenance of standard operating processes, workflows, templates, and other tools to improve consistency and efficiency across Technical Development
• Assist with capacity and resource planning by collecting and maintaining data related to laboratory utilization, equipment needs, and upcoming development activities
• Compile operational metrics and identify trends or recurring issues that may inform process improvements
• Identify opportunities to improve day-to-day Technical Development operations and support the development of practical tools, processes, and ways of working that increase efficiency and visibility.
• Other related duties, as assigned

Requirements

• Bachelor's degree in life sciences or related discipline; equivalent relevant experience may be considered
• Approximately 2-3 years of experience in biotechnology or pharmaceutical laboratory operations
• Strong interpersonal skills and ability to work effectively with scientists, engineers, and cross-functional stakeholders
• Proficiency with Microsoft Office applications, particularly Excel, PowerPoint, Outlook, and Teams; experience with project management, inventory, or laboratory management systems is a plus.
• Strong organizational and project coordination skills with the ability to manage multiple activities, priorities, and timelines
• Demonstrated attention to detail and ability to maintain accurate records, trackers, schedules, and documentation.
• Proactive, solutions-oriented approach with an interest in identifying opportunities to improve processes and ways of working.
• Ability to anticipate needs, follow through on commitments, and escalate potential issues or constraints appropriately.
• Comfortable working in a fast-paced, evolving environment where processes may still be developing.

Qualifications

• Experience supporting laboratory-based scientific or technical organizations
• Ability to anticipate operational constraints and proactively develop solutions
• Experience working in regulated biotechnology or pharmaceutical environment
• Exposure to cell & gene therapy

Benefits

Our most important asset is our people, and we offer competitive benefits, PTO, and stock option plans.