Supply Chain Manager, Materials Management and Planning

About Us

Obsidian Therapeutics is pioneering engineered cell and gene therapies to deliver transformative outcomes for patients. Obsidian’s programs apply our cytoDRiVE® technology in Cell and Gene therapy products to control expression of proteins for enhanced therapeutic efficacy and safety. Obsidian’s lead program is currently in clinical development for the treatment of patients with metastatic melanoma and non-small cell lung cancer. We’re proud of our diverse talented team and committed to cultivating an environment of inclusion where each person feels a strong sense of belonging and is supported to continuously learn and contribute their best work. Our Research team is based in the heart of Cambridge, MA, and Technical Operations team is based in our purpose built facility in Bedford, MA. Obsidianites enjoy a highly collaborative culture, competitive salary and benefits, and potential for ownership through stock options.

The Opportunity

We are looking for a highly motivated Supply Chain Manager with a strong background in supply planning, inventory management, and supplier relationship management within cGMP-regulated virtual manufacturing environments. As a key individual contributor within our Technical Operations team, you will lead material management activities in support of our clinical trials and broader CMC roadmap helping to drive the development of our first clinical stage autologous cell therapy program targeting solid tumors.

You Will...

• Manage an End-to-End inventory management program through collaboration with external partners (Contract Manufacturing Organizations, External Biorepositories, Logistic Partners).
• Manage a detailed End-to-End MRP process including the establishment of risk-based inventory targets.
• Develop and manage a Sample inventory management program in partnership with Analytical Development and Quality Control groups.
• Support the S&OP process through End-to-End supply planning and scenario analysis.
• Support Raw Material risk assessment and Raw Material Qualification activities as part of BLA readiness activities.
• Support the establishment of a supplier management program including the development of a sourcing strategy and the establishment of Supply Agreements.
• Contribute to the development of a formal label management program.
• Develop and maintain appropriate GMP controlled documents (i.e., SOPs, WIs, and Forms).
• Manage the sourcing of Tumor Tissue to support development activities.
• Career Growth Opportunities: Rich career growth opportunities.

You Bring...

• Bachelor’s Degree in Life Sciences, Supply Chain Management, or related discipline; advanced degree preferred.
• 6+ years of relevant experience in inventory management, planning, or supply chain in a biotech or pharmaceutical company, preferably in handling cell therapy or other similarly complex products.
• Extensive quality and compliance background in a clinical GMP operational environment, including 3+ years prior experience in commercial or clinical GMP environment.
• Ability to execute strategic objectives by focusing on critical near-term priorities while building toward long-term supply chain robustness for reliable delivery of complex treatments to patients.
• Excellent analytical and problem-solving skills, with the ability to interpret complex data, make data-driven decisions, and clearly articulate business rationale and implications.
• Excellent planning, coordination, and time management skills; You translate high level goals into plans, collaborate and adapt to meet objectives and timelines.
• Excellent oral, written, and visual communication skills. You listen to understand and communicate effectively and persuasively with partners, colleagues, and leadership.
• A desire and ability to work in a dynamic, collaborative environment; you build productive and healthy relationships within and across functions, Collaborative and accountable – recognizes success requires teamwork and interdisciplinary thinking; you share feedback and constructively challenge and accept challenges to generate the best ideas to advance project and company goals.
• Self-motivated, with a proven ability to meet objectives, timelines, and high standards managing multiple responsibilities in parallel.
• Flexible – able to operate and adapt in a fast paced, rapidly developing environment Curious and humble – seeks and welcomes input/expertise of others, continuous learner Tenacious and resilient – is not easily overwhelmed by challenges, delivers on commitments, operates with urgency.

Bonus Qualifications

• Strong knowledge of managing temperature controlled cold chains including 2-8C, -80C, and LN2 preferred: Prior experience in managing such shipments in collaboration with logistics partners.
• Experience with Autologous Cell Therapy.

Compensation

The anticipated base salary range for this role is $115,500—$141,000 USD. Obsidian is committed to equitable and transparent pay practices. The actual base salary offered will be determined based on a combination of factors, including applicable qualifications, level of education, the depth of experience, unique skills, geographic location, internal equity, and/or business needs. The actual base salary offered will be in accordance with federal, state, and/or local wage requirements for the role’s location.