Staff Research Associate II

About the role

The incumbent will conduct tumor studies in select mouse models, focusing on orthotopic brain tumor implantation with and without radiosensitizing nanoparticle conjugates. Responsibilities include stereotactic live animal surgery, conformal irradiation procedures, and imaging. Additional duties involve preparing, imaging, and analyzing brain and tumor tissues for immune profiling, generating fixed and frozen tissue sections, performing behavioral tests, maintaining breeding colonies, and supporting general lab tasks.

Responsibilities

• Conduct tumor studies in mouse models
• Immunohistological techniques
• Tissue handling and cryostat sectioning
• Confocal and fluorescent microscopic techniques
• Data quantification using in-house/core software platforms
• Maintain breeding colonies and genotyping of transgenic mice
• Behavioral testing using video recording and specialized analysis software
• Support general lab duties such as reagent preparation, cleaning, and dishware

Requirements

• Familiarity with small animal (mouse) handling
• Laboratory experience utilizing the techniques and methods itemized above
• Experience working independently
• Experience in assisting, testing, and standardizing immunohistological techniques
• Experience in tissue handling and cryostat sectioning
• Experience in use of confocal and fluorescent microscopic techniques to assess neural stem/precursor cell populations
• Experience in use of routine statistical, data plotting programs

Qualifications

• Radiobiology background preferred

Skills

• Behavioral testing involving rodents

Benefits

Details of benefits can be found here.

Pay

Salary range listed below.

Schedule

Flexibility in the work schedule is a must, as some experiments will require work at abnormal hours or over weekends.

Special Conditions

• Willingness to travel
• Background check and Live Scan
• Employment Misconduct*
• Legal Right to work in the United States
• Vaccination Policies
• Smoking and Tobacco Policy
• Drug Free Environment
• Misconduct Disclosure Requirement

For more information, please contact Human Resources at (949) 824-0500 or eec@uci.edu.