Jobs · Research

Staff Bioinformatics Scientist -- Oncology/MRD Algorithm Development

Illumina · San Diego, CA · 3 wk ago
RemoteRemoteResearch$156k–$233k/yrFull-time
We need to output HTML fragment with sections: headings

for sections like About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. Use
  • for any list of duties/requirements/benefits, and

    for prose. Do NOT repeat job title as heading. Do NOT put Job ID/requisition numbers as headings. Remove boilerplate, navigation, legal, EEO, equal-opportunity, scam-warning, duplicated lines, application instructions. Include a section ONLY when posting has real, specific content for it — never emit heading followed by filler/placeholder text. Prefer few substantive sections over many thin ones. We need to extract substantive content: The posting includes: - Intro paragraph about Illumina mission etc. Could be "About the role" or maybe "About Illumina". But we need to decide sections. We have sections: "Why Us", "Why You", "The Role", "Responsibilities", "Requirements", then salary/pay, benefits, etc. We need to map to allowed headings: About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. We can combine some. We need to preserve all substantive info, not invent. Let's parse content: Intro: "What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible." That's about Illumina and role. Could go under "About the role". Next: "Why We are a multi-disciplinary and multinational team focused in using next-generation sequencing technology to transform human health and save patient’s lives. Our team works at the interface of research and clinical practice developing and improving innovative algorithms to biomarkers and variants that fill gaps in clinical practice, focusing primarily on oncology. We collaborate deeply with internal and external teams, to augment DRAGEN, Illumina’s software platform to analyze high-throughput sequencing data, remove barriers for its use in clinical settings, and develop new biomarkers in areas such as MRD and methylation." That's also about team, could be part of About the role. Next: "Why You We know the importance of your role and offer you a collaborative and supportive environment in which you are actively encouraged to develop your skills and knowledge. Illumina's mission is to improve human health by unlocking the power of the genome - if that inspires you, let's talk. If you are excited as we are about using genomics to transform the practice of medicine, have a proven track record of algorithm development, data analysis, and strong coding ability, this is the role for you. You will be part of a culture fueled by innovation, collaboration, and openness." That's about candidate fit, could be part of About the role or maybe "Qualifications"? But we have separate sections. Next: "To be successful as a Staff Bioinformatics Scientist, you will need a background in bioinformatics with a particular focus on algorithm development, biomarkers and oncology. Previous experience with at least two: statistics, common bioinformatics methods, next generation sequencing analysis, and oncology will be key to your success. This role may be performed remotely within the US but the position requires accommodation to meeting times to overlap with Pacific time zone hours." That's requirements/qualifications. Next: "The Role The Staff Bioinformatics Scientist will drive the development of algorithms for detecting minimal residual disease in ctDNA samples using signals from small variant calling, copy number calling, fragmentomics, and methylation. This role will also assist in improving algorithms for therapy selection across a range of variant types and biomarkers." That's role description. Next: "Responsibilities Prototype novel NGS algorithms for clinical oncology use cases such as MRDAssess and improve existing secondary analysis algorithms for variant and biomarker detectionIn collaboration with external and internal experimental teams, design and analyze experiments to support existing or new Illumina oncology assays.Provide technical guidance to internal and external collaborators.Participate in cross functional assay and algorithm R&D teams with minimal oversight.Effectively communicate plans and results across functions" We need to split responsibilities into list items. Next: "Requirements PhD in bioinformatics, computation biology, statistics, math or related field with 3+ years industry experienceFluency in at least two of statistics, common bioinformatics methods NGS analysis, and oncology.Proven track-record with developing bioinformatics NGS algorithms beyond leveraging already existing tools.Fluency in programming languages such as Python. Experience with C++ is desiredGood communication skills to contribute to cross functional project teams and work with stakeholders." That's requirements list. Next: "The estimated base salary range for the Staff Bioinformatics Scientist -- Oncology/MRD Algorithm Development role based in the United States of America is: $155,600 - $233,400. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable cash programs (bonus or commission) and eligible roles may receive equity as part of the compensation package." That's Pay section. Next: "We offer a wide range of benefits as innovative as our work, including access to genomics sequencing, family planning, health/dental/vision, retirement benefits, and paid time off." That's Benefits. Next: "We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility." That's more about culture, could be part of About the role or maybe Benefits? But it's not benefits per se. Could be part of About the role. We also have EEO statement etc which we must remove. We also have background check, AI prohibition, accommodation contact, etc - remove as boilerplate. We also have "The position will be posted until a final candidate is selected or the requisition has a sufficient number of qualified applicants." - remove. We need to avoid duplication. Now decide sections: - About the role: combine intro, Why Us, Why You, culture statements. - Responsibilities: list. - Requirements: list (PhD, experience, fluency, etc.) - Qualifications: maybe same as Requirements? But we have both Requirements and Qualifications headings allowed. Could split: Requirements = mandatory (PhD, experience, fluency), Qualifications = desired (C++ experience, good communication skills). But we need to avoid thin sections. Perhaps combine into Requirements section only, as we have enough content. - Skills: maybe list programming languages (Python, C++ desired) and communication skills. - Benefits: list. - Pay: salary range and variable cash/equity. - Schedule: maybe mention remote within US but need accommodation to meeting times overlapping Pacific time zone. That's schedule info. Could be a Schedule section. We need to ensure we don't create sections with filler like "commensurate with experience". We have actual content. Let's extract precise text. About the role: We'll combine paragraphs: "What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Why We are a multi-disciplinary and multinational team focused in using next-generation sequencing technology to transform human health and save patient’s lives. Our team works at the interface of research and clinical practice developing and improving innovative algorithms to biomarkers and variants that fill gaps in clinical practice, focusing primarily on oncology. We collaborate deeply with internal and external teams, to augment DRAGEN, Illumina’s software platform to analyze high-throughput sequencing data, remove barriers for its use in clinical settings, and develop new biomarkers in areas such as MRD and methylation. Why You We know the importance of your role and offer you a collaborative and supportive environment in which you are actively encouraged to develop your skills and knowledge. Illumina's mission is to improve human health by unlocking the power of the genome - if that inspires you, let's talk. If you are excited as we are about using genomics to transform the practice of medicine, have a proven track record of algorithm development, data analysis, and strong coding ability, this is the role for you. You will be part of a culture fueled by innovation, collaboration, and openness. We are a company deeply rooted in belonging, promoting an inclusive environment where employees feel valued and empowered to contribute to our mission. Built on a strong foundation, Illumina has always prioritized openness, collaboration, and seeking alternative perspectives to propel innovation in genomics. We are proud to confirm a zero-net gap in pay, regardless of gender, ethnicity, or race. We also have several Employee Resource Groups (ERG) that deliver career development experiences, increase cultural awareness, and offer opportunities to engage in social responsibility." That seems substantive. Responsibilities: list items: - Prototype novel NGS algorithms for clinical oncology use cases such as MRD - Assess and improve existing secondary analysis algorithms for variant and biomarker detection - In collaboration with external and internal experimental teams, design and analyze experiments to support existing or new Illumina oncology assays. - Provide technical guidance to internal and external collaborators. - Participate in cross functional assay and algorithm R&D teams with minimal oversight. - Effectively communicate plans and results across functions Note: The original had "Prototype novel NGS algorithms for clinical oncology use cases such as MRDAssess and improve existing secondary analysis algorithms for variant and biomarker detection" but we split. Requirements: list: - PhD in bioinformatics, computation biology, statistics, math or related field with 3+ years industry experience - Fluency in at least two of statistics, common bioinformatics methods, NGS analysis, and oncology. - Proven track-record with developing bioinformatics NGS algorithms beyond leveraging already existing tools. - Fluency in programming languages such as Python. Experience with C++ is desired - Good communication skills to contribute to cross functional project teams and work with stakeholders. We could separate Skills: Python, C++ desired, communication skills. But we already have communication skills in Requirements. Could move communication skills to Skills. Let's decide: Requirements = education/experience, fluency in stats/bioinformatics/NGS/oncology, proven track-record developing algorithms. Skills = programming languages (Python, C++ desired) and communication skills. Qualifications maybe not needed. Benefits: list: - Access to genomics sequencing - Family planning - Health/dental/vision - Retirement benefits - Paid time off Pay: paragraph: "The estimated base salary range for the Staff Bioinformatics Scientist -- Oncology/MRD Algorithm Development role based in the United States of America is: $155,600 - $233,400. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the role; therefore, most candidates are hired between the minimum and middle of the range. Placement depends on experience, skills, location, and internal equity. Additionally, all employees are eligible for one of our variable

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