Sr. Technical Program Manager, AI Security

The Role

Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of AI-readiness initiatives at Moderna globally. The ideal candidate will have a high level of integrity and personal accountability, strong interpersonal skills, and infrastructure technology domain expertise.

Here’s What You’ll Do

• Program Management – take a structured, data-driven, and risk-based approach to program scoping, execution, and reporting
• Kick off and successfully manage multiple, simultaneous, complex, high visibility workstreams with full ownership, effective collaboration, and good process
• Build processes, templates, and structure, or leverage existing ones as appropriate
• Manage vendors, schedule, scope, and cost
• Measure program success (or lack thereof) and risks using data and facts
• Provide balanced risk remediation strategies and recommendations and drive risk mitigation
• Develop and maintain close stakeholder relationships and build influence to drive the appropriate outcomes across Moderna
• Provide clear, accurate, consistent, and timely communications
• Advance good infrastructure and security practices and culture
• Partner Collaboration - work with Cybersecurity, Builder Tools & Platforms, Infrastructure, Identity & Endpoint Engineering, GRC, AI Engineering, Data, Enablement/L&D, software engineering, and business stakeholders to manage and drive improvement projects in a structured and predictable manner
• Manage multiple initiatives to oversee the architecture and lifecycle of enterprise AI systems, including agent identity, tool authorization, and secure development practices; to drive governance frameworks that define permitted AI use, contextual standards, and regulatory alignment — including GxP where applicable; and to ensure end-to-end observability and monitoring of AI agents in production.
• Own the operating model for AI enablement programs, including pilots, cohorts, and phased rollouts, and partner with Enablement/L&D teams to shape role-based learning paths for AI builders
• Actively contribute to creating a more inclusive culture and environment at Moderna; endorse, create, and maintain antiracist policies and processes

Here’s What You’ll Need (Minimum Qualifications)

• Experience: 8+ years in Technical Program Management, Engineering Program Management, or similar roles in AI/ML-heavy environments
• Technical Depth: Strong understanding of AI/ML systems, including model training pipelines, LLMs, MLOps, data pipelines, and cloud infrastructure
• Strong understanding of AI/ML development workflows, AI-assisted engineering tools, or modern software development platforms
• Demonstrated technical depth, problem-solving capabilities, and stakeholder and vendor management skills
• Experience in running programs within a cross-functional, global team of mixed engineering, architecture, and operations
• Able to successfully scope and drive complex and multi-workstream programs in a structured, risk-considerate, data-driven fashion
• Experience improving developer productivity and building internal tools/platforms
• Ability to define metrics, analyze tradeoffs, and drive decisions with data
• Strong listener with the ability to deeply understand, ask the right questions, and proactively pursue constructive feedback
• Proven ability to operate in highly matrixed environments and influence without direct authority
• Excellent written and verbal communication skills, including executive-level storytelling

Here’s What You’ll Bring to the Table (Preferred Qualifications)

• Background in software engineering, data science, or machine learning
• Experience with LLM platforms, prompt engineering workflows, or AI copilots
• Experience with AI development platforms, copilots, developer tooling, or MLOps concepts
• Experience with responsible AI, model governance, or compliance frameworks
• Experience driving structured, process-driven AI transformation initiatives
• Familiarity with tools such as Kubernetes, Airflow, MLFlow, or similar MLOps stacks
• Familiarity with governed enablement models (e.g., citizen development, platform standards, golden paths)
• Knowledge of security and compliance standards relevant to AI and AI-assisted engineering
• Influential, inclusive, and trusted partner compassionate to the needs and situations of all your stakeholders
• Embrace a culture of continuous service improvement and service excellence
• A desire to make an impact as part of a high-growth, transformational company
• Experience with GxP environments and regulatory requirements

Pay & Benefits

At Moderna, we believe that when you feel your best, you can do your best work. That’s why our US benefits and global well-being resources are designed to support you—at work, at home, and everywhere in between.

• Best-in-class healthcare coverage, plus voluntary benefit programs to support your unique needs
• A holistic approach to well-being, with access to fitness, mindfulness, and mental health support
• Family planning benefits, including fertility, adoption, and surrogacy support
• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investment opportunities to help you plan for the future
• Location-specific perks and extras

About Moderna

Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.

Our Working Model

We believe an in-person culture is critical to our success. Moderna champions the significant benefits of in-office collaboration by embracing a 70/30 work model. This 70% in-office structure helps to foster a culture rich in innovation, teamwork, and direct mentorship. Join us in shaping a world where every interaction is an opportunity to learn, contribute, and make a meaningful impact.

Equal Opportunities

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law.

Accommodations

We’re focused on attracting, retaining, developing, and advancing our employees. By cultivating a workplace that values diverse experiences, backgrounds, and ideas, we create an environment where every employee can contribute their best.

Export Control Notice

This position may involve access to technology or data that is subject to U.S. export control laws, including the Export Administration Regulations (EAR). As such, employment is contingent upon the applicant’s ability to access export-controlled information in accordance with U.S. law. Due to the nature of the work and regulatory requirements, only individuals who qualify as U.S. persons (citizens, permanent residents, asylees, or refugees) are eligible for this position. For this role Moderna is unable to sponsor non-U.S. persons to apply for an export control license.