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Jobs · Analyst · New York

Sr Scientist, Biologics Characterization

Regeneron · Tarrytown, NY · 2 wk ago
On-siteAnalyst$110k–$179k/yrFull-time

About the role

Regeneron’s Product Biochemistry in Tarrytown, NY is seeking a motivated and innovative Senior Scientist to drive late-stage development (Phase II through commercialization) of biologics. You will develop and deploy analytical methods and purification strategies, enrich and characterize product variants, and help onboard new technologies that deepen product understanding and improve processes across the pipeline.

Responsibilities

  • Develop analytical methods and purification protocols to support extended characterization of therapeutic proteins and gene therapy vectors.

  • Conduct biochemical/biophysical characterization to support development, regulatory submissions, and commercialization.

  • Apply DOE, advanced statistics, and risk assessments to evaluate and optimize methods and processes.

  • Author high-quality technical documents (protocols, reports, memos) and contribute to regulatory sections and publications.

  • Ensure timely documentation of experiments following established SOPs and guidelines.

  • Maintain instruments, troubleshoot issues, and improve lab/data workflows within your area of expertise.

  • Adhere to procedures, guidance, and best practices to ensure lab safety.

  • Proactively identify process improvement opportunities across Product Biochemistry and Regeneron and help drive implementation.

Requirements

  • Strong lab skills in protein separation, purification, and tangential flow filtration (TFF).

  • Skills in protein/product identification using mass spectrometry.

  • Ability to thrive in a fast-paced, team environment and work independently across multiple projects.

  • Initiative, calculated risk-taking, and passion for innovation and continuous improvement.

  • Excellent oral and written communication skills and evidence of teamwork.

Qualifications

  • BS/MS/Ph.D. in Biochemistry/Biophysics, or related field.

  • 8-10 years of proven experience (BS/MS) or 0-2 years of proven experience (Ph.D.).

  • Technical proficiency in automated FPLC and/or HPLC (SEC, IEX, affinity), electrophoresis (capillary or microchip, SDS-PAGE, western blots), spectroscopy and light scattering.

  • A fundamental understanding of protein structure/function, mass spectrometry, and immunology/immunogenicity.

Skills

  • Experience working in the biopharmaceutical industry.

Benefits

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits.

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