Sr Scientist, Biologics Characterization

About the role

Regeneron's Product Biochemistry in Tarrytown, NY is seeking a Senior Scientist to drive late-stage development (Phase II through commercialization) of biologics. Key responsibilities include developing and deploying analytical methods and purification strategies, conducting biochemical/biophysical characterization, applying DOE and advanced statistics, authoring technical documents, maintaining instruments, troubleshooting, identifying process improvements, and mentoring.

Responsibilities

• Develop analytical methods and purification protocols to support extended characterization of therapeutic proteins and gene therapy vectors.
• Conduct biochemical/biophysical characterization to support development, regulatory submissions, and commercialization.
• Apply DOE, advanced statistics, and risk assessments to evaluate and optimize methods and processes.
• Author high-quality technical documents (protocols, reports, memos) and contribute to regulatory sections and publications.
• Maintain instruments, troubleshoot issues, and improve lab/data workflows within your area of expertise.
• Proactively identify process improvement opportunities across Product Biochemistry and Regeneron and help drive implementation.

Requirements

• Bachelor's Degree in Biochemistry/Biophysics or related field.
• 8-10 years of proven experience (BS/MS) or 0-2 years of proven experience (Ph.D.) in a biopharmaceutical setting.
• Strong lab skills in protein separation, purification, and tangential flow filtration (TFF).
• Skills in protein/product identification using mass spectrometry.

Qualifications

• Technical proficiency in automated FPLC and/or HPLC (SEC, IEX, affinity).
• Fundamental understanding of protein structure/function, mass spectrometry, and immunology/immunogenicity.

Skills

• Scientific creativity.
• Hardworking and efficient.
• Flexible and able to perform key responsibilities in a fast-paced, team environment.
• Initiative, calculated risk-taking, and a passion for innovation and continuous improvement.
• Excellent oral and written communication skills.
• Evidence of teamwork.

Benefits

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit this link.

Pay

$109,900.00 - $179,300.00 annually

Schedule

Full time