Sr. Research Associate, RNA Innovation

Moderna is seeking a Senior Research Associate for the RNA Innovation team in Cambridge, MA. In this early research laboratory-based position, the candidate will focus on the chemical biology of mRNA, discovering and characterizing how RNA modifications impact RNA metabolism and performance.

About the role

The researcher will design and plan experiments implementing in vitro biochemical approaches as well as cell line techniques to investigate mRNAs of interest. The role requires a high level of initiative, ownership, and the ability to drive projects forward with urgency. Prior academic or industrial experience in a laboratory focusing on RNA is strongly preferred. Ideal candidates should have a strong interest in the biochemistry of nucleic acids, enjoy working in a dynamic environment, and be flexible in working both individually and within cross-functional teams.

Responsibilities

• Develop and execute methods to study the stability and translation of modified mRNA using cell lines and in vitro biochemistry
• Implement analytical approaches such as RT/qPCR, chromatography, and mass spectrometry to analyze RNAs
• Develop and execute Next Generation Sequencing library preparation protocols
• Maintain cell lines, equipment, scientific records, and an organized lab space
• Communicate scientific findings to colleagues and collaborators in formal and informal settings

Requirements

• MS in Biochemistry, Chemical Biology, Chemistry, Molecular Biology, Chemical Engineering, or closely related field with 2+ years of experience (3-5 years preferred)
• Knowledge of biochemistry/chemical biology of nucleic acids
• Experience working with RNA
• This position is site-based in Cambridge, MA and requires full-time on-site work; remote work is not eligible
• Must already hold work authorization in the US and be able to maintain that status without future sponsorship

Qualifications

• Experience with mammalian cell culture and relevant techniques
• Experience with analytical approaches relevant to RNA (e.g., gel electrophoresis, qPCR, Next Generation Sequencing, chromatography)
• Excellent interpersonal, organizational, and collaborative skills, with strong attention to detail
• Ability to quickly master new scientific techniques and concepts
• Excellent record-keeping
• Desire to make an impact as part of a high-growth, transformational company

Benefits

• Competitive healthcare, plus voluntary benefit programs to support unique needs
• Holistic well-being support, including fitness, mindfulness, and mental health resources
• Family planning benefits, including fertility, adoption, and surrogacy support
• Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown
• Savings and investments to help plan for the future
• Location-specific perks and extras

Pay

The salary range for this role is $74,000.00 - $118,400.00. An individual’s position within the salary range will be based on factors including competencies, education, qualifications, certifications, experience, skills, performance, and business needs. The successful candidate may also be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance.