Research Associate RA/Sr. RA - RNA Process Development and Manufacturing

Addition Therapeutics is advancing transformative therapies using its proprietary PRINT™ (Precise RNA-mediated Insertion of Transgenes) platform, enabling RNA-only therapeutics to insert genetic elements into specific safe harbor genome sites. Based in South San Francisco, our team drives scientific breakthroughs in a dynamic culture focused on patient impact.

About the Role

• Produce RNA in small to mid-scale reactions
• Prepare reagents, sub-aliquot, maintain reagent logs, and manage inventory
• Support reagent selection and vendor qualification
• Contribute to creating and documenting protocols and techniques
• Collaborate with the analytical team to assess purity and impurity levels in DNA/RNA products
• Support QC assays
• Collect and prepare accurate data summaries; review written reports
• Stay current with scientific literature and implement new techniques to improve quality/efficiency

Requirements

• Bachelor’s or master’s degree in chemistry, biochemistry, or related field with 2–4 years of experience
• Experience with manufacturing DNA, RNA, or gene therapy-related modalities (GMP or non-GMP)
• Strong documentation practices, including electronic notebooks
• Thrives in a fast-moving, results-oriented startup environment
• Self-motivated, passionate, and eager to learn
• Experience with external vendor communications

Skills

• Tangential flow filtration, AKTA purification, and bioreactors (significant plus)
• QC assays: Qubit, Fragment Analyzer, LAL Endotoxin (significant plus)
• Hands-on experience in molecular and cell biology
• Familiarity with JMP statistical software

Pay

Hourly rate: $55–$70

Location: South San Francisco, California