Sr. Research Associate, Delivery

Position Summary

AskBio is seeking a highly motivated, enthusiastic, and collaborative Senior Research Associate to support the development and discovery of next-generation gene therapies utilizing state-of-the-art non-viral delivery technologies.

Job Responsibilities

• Perform plasmid purification, genomic DNA extraction, RNA extraction, and PCR-based assays (PCR, qPCR, ddPCR)
• Conduct small-scale LNP formulation and analytical characterization for early research and preclinical in vivo and in vitro studies
• Perform in vitro cell-based assays, including plasmid transfection, AAV transduction, LNP transfection, and primary cell culture
• Analyze data and effectively communicate results through formal reports and presentations for internal and external stakeholders
• Develop detailed experimental protocols and maintain an electronic laboratory notebook in accordance with good documentation and data integrity practices
• Maintain inventory and order reagents and materials to support timely project execution
• Ensure laboratory areas are clean, organized, and adequately stocked with necessary equipment and supplies

Minimum Requirements

• Bachelor’s degree in molecular biology, Biochemistry, or a related field with 5+ years of research experience; OR a Master’s degree in molecular biology, Biochemistry, or a related field with 2+ years of research experience
• Hands-on experience with molecular biology techniques, including DNA/RNA isolation, SDS-PAGE, qPCR, and Western blot
• Clear understanding of in vivo gene therapy approaches, including adeno-associated virus (AAV) and lipid nanoparticles (LNP)
• Experience with cell line maintenance, including primary cell culture
• Strong technical laboratory skills with the ability to independently execute protocols and experiments
• Ability to manage multiple projects simultaneously and work independently in a fast-paced, collaborative environment
• Highly organized, self-motivated, and able to work both independently and within cross-functional teams
• Excellent written and verbal communication skills, including accurate documentation practices
• Proficiency in Microsoft Office Suite (Word, Excel, PowerPoint)
• Strong problem-solving skills and sound scientific judgment

Preferred Education, Experience And Skills

• Experience with research-grade LNP formulation and analytical characterization
• Experience with next-generation sequencing (NGS)
• Understanding of statistics and data analysis/interpretation
• Experience using SnapGene and GraphPad