Sr. Program Manager, Breakthrough Bio

Position Summary

The Sr. Manager of Programs leads the design and delivery of Breakthrough Bio, a global accelerator for elite healthcare and life sciences startups. This role involves developing and recommending structured program models, drafting operational playbooks, and working with small agile teams.

What You'll Do

• Program Management
• Support the structure, execution, and continuous improvement of Breakthrough Bio across all program phases, ensuring alignment with MassChallenge's strategic goals
• Develop and implement operational playbooks that standardize and scale program processes
• Serve as a key liaison between startups, corporate partners, mentors, and internal teams to drive program success
• Collaborate with small, modular teams to execute program components efficiently and effectively
• Represent MassChallenge at industry events, facilitate workshops, and participate in panel discussions or public speaking engagements
• Identify and address pain points for founders, judges, and mentors, recommending scalable solutions that enhance the program experience
• Ensure programs meet or exceed NPS and CSAT targets, using data to refine program execution and improve the startup experience
• Support business development efforts by identifying partnership opportunities, maintaining stakeholder pipelines, and contributing to proposal development and partner engagement
• Founder Experience Metrics
• Manage multi-phase, hybrid program logistics including virtual and in-person components across time zones
• Support institutional or government partner reporting
• Continuous Improvement
• Support initiatives that enhance DEI across all programs, ensuring equitable access and support for underrepresented founders

Who You Are & What You Bring

• Education & Experience Requirements
• 3+ years of experience in program management, startup support, or innovation ecosystem leadership, with a strong cross-functional and multi-program track record
• Adept in program design, operations, and execution, with experience developing playbooks and managing scalable processes
• Strong relationship-building and communication skills, with a growing network in the startup and innovation ecosystem
• Data-driven and strategic mindset, with the ability to assess program impact through NPS, CSAT, CES, and other performance metrics
• Passion for entrepreneurship and a commitment to fostering an inclusive environment that supports diverse founders and innovators
• Comfort with public speaking and external representation, including participating in panels, facilitating discussions, and engaging with key stakeholders
• Familiarity with the healthcare, life sciences, medtech, or biotech sector is a plus

Who We Are

MassChallenge is the global network for innovators who are working to solve massive challenges. We connect startups, experts, corporations, and communities to grow and transform businesses and economies. At MassChallenge we:

• Help entrepreneurs build the next generation of transformational businesses by connecting them with the resources, partnerships, and communities that help them launch, grow, and scale their startups.
• Help our partners build, grow, and evolve their corporate innovation practices.
• Leverage the power of entrepreneurship to strengthen global innovation ecosystems.

Why You Should Join Us

• We believe working at MassChallenge is fulfilling because of the mission, challenging because of the pace and work, and rewarding because you get to build to the next step in your career here.
• You join an incredible team and network of innovators and entrepreneurs, focus on impact and output, and help strengthen the global innovation ecosystem.
• Our Core Values: Founder Mindset: Optimism, Tenacity, Love the Problem; Connect & Collaborate: Empathy & Inclusion & Fun, Build Community, Connect the Dots; Progress over Perfection: Build on experience, Fail Fast, Demonstrate Traction.