Jobs · Healthcare

Sr Director, Medical Affairs (Obesity and Metabolic Programs)

Structure Therapeutics · South San Francisco, CA · 3 wk ago
Healthcare$260k–$360k/yrFull-time

Position Summary

Reporting to the Executive Director, Medical Affairs & Advocacy Engagement, the Sr Director, Medical Director at Structure Therapeutics will lead the development and execution of the Medical Strategy, gathering and synthesizing external insights—including treatment patterns, unmet medical needs, and competitive intelligence—across all metabolic programs. This role is critical in shaping scientific engagement and communications, identifying evidence gaps, and supporting lifecycle management. The individual will serve as a key scientific expert internally and externally, ensuring alignment across clinical development, regulatory, and commercial readiness efforts. As a trusted scientific partner, the Medical Director builds and sustains relationships with key opinion leaders, investigators, healthcare professionals, and patient communities, facilitating the exchange of scientific information related to the company’s pipeline and therapeutic focus areas.

Job Responsibilities

  • Develop and execute a comprehensive Medical Strategic Plan, including insight generation, data dissemination, and medical communications, across all obesity and related metabolic programs

  • Lead Publication Strategy across all programs (abstracts, manuscripts, congress presentations)

  • Scientific & External Engagement

    • Build relationships with Key Opinion Leaders (KOLs), academic institutions, and healthcare providers
    • Present clinical and scientific data on metabolic therapies
    • Represent the company at medical and community congresses, advisory boards
    • Lead high-level scientific discussions on disease state and treatment landscape
  • Evidence Generation & Insights

    • Support Investigator-Initiated Trials (IITs) and real-world evidence studies
    • Gather and synthesize medical insights from HCP interactions
    • Inform clinical development plans and lifecycle management
  • Cross-Functional Collaboration

    • Partner with:
      • Clinical development (trial design considerations, medical insights, unmet medical need)
      • Clinical Operations (investigator needs and engagement)
      • Market access (value messaging)
      • Commercial teams (compliant scientific support)
    • Review materials for scientific accuracy and compliance as representative in Medical Legal Regulatory (MLR) review process
    • Ensure all activities comply with regulatory and ethical standards

    Qualifications

    • Education

      • MD, PharmD, or PhD in a relevant scientific field
    • Experience

      • 10+ years in biotech/pharma
      • Strong background in metabolic diseases (e.g., obesity, type 2 diabetes), global experience a plus
      • Prior experience as Medical Director or equivalent in Medical Affairs
    • Skills

      • Deep scientific expertise in metabolism
      • Direct experience in obesity, type 2 diabetes, or incretin-based therapies is preferred
      • Experience with protocol design in metabolism, particularly incretin therapies
      • Strong communication and presentation skills
      • Leadership and team management ability
      • Strategic thinking with execution focus
    • Travel Required

      • Regional or national coverage
      • Travel (25%) for HCP engagement and conferences, corporate meetings

    Benefits

    • Medical, dental, and vision insurance

    • 401k match

    • Unlimited PTO

    • A number of paid holidays including winter shutdown

    Notice to Recruiters/Staffing Agencies

    Recruiters and staffing agencies should not contact Structure Therapeutics through this page. All recruitment vendors (search firms, recruitment agencies, and staffing companies) are prohibited from contacting our hiring manager(s), executive team members, or employees. We require that all recruiters and staffing agencies have a fully executed, formal written agreement on file.

    Fraud Alert

    To all candidates: your personal information and online safety are a top priority for us. At Structure Therapeutics, direct candidates to apply through our official career page at BambooHR. Recruiters will always contact you using the domain of Structuretx.com. We will never request payments, ask for financial account information or sensitive information like social security numbers. If you are unsure if a message is from Structure Therapeutics, please email human resources.

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