Sr. Director, Epidemiology & RWE Analytics

Neurocrine Biosciences is a leading biopharmaceutical company dedicated to discovering, developing, and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine, and immunological disorders. With FDA-approved treatments and a robust pipeline, we apply our expertise in neuroscience to ease the burden of debilitating diseases and disorders.

About The Role

Provides senior leadership for enterprise-wide epidemiology and real-world evidence (RWE) strategy, governance, and execution across therapeutic areas and portfolios. Accountable for defining and delivering fit-for-purpose, consistent evidence strategies that support clinical development, regulatory submissions, medical affairs, and market access. Serves as a senior thought partner to R&D, Medical, Market Access, and Analytics leadership and leads teams responsible for high-impact, externally facing epidemiologic and RWE programs.

Responsibilities

• Define and lead enterprise-wide epidemiology and RWE strategy, ensuring alignment with corporate objectives and cross-functional priorities across R&D, Medical, Market Access, and Analytics.
• Establish and oversee functional governance, including methodological standards, evidence quality expectations, prioritization frameworks, and ways of working across therapeutic areas.
• Translate enterprise RWE strategy into portfolio- and therapeutic-area-level evidence plans supporting development, launch, and lifecycle management.
• Serve as a senior advisor to executive and cross-functional leadership on population health, disease epidemiology, and real-world evidence.
• Drive evidence strategies that directly support regulatory submissions, HTAs, reimbursement decisions, and global value demonstration.
• Lead, coach, and develop Directors, Managers, and senior scientific staff; ensure effective talent development and succession planning.
• Oversee functional resourcing and budget management to ensure efficient, compliant, and high-quality execution.
• Partner closely with R&D leadership to integrate RWE into Phase 3 trial design and late-stage development, including external control arms, endpoint validation, and contextualization of clinical outcomes.
• Provide functional scientific accountability for epidemiology and RWE components of late-stage development programs.
• Ensure rigorous epidemiologic and observational methodologies are applied consistently across programs.
• Collaborate with Drug Safety and Pharmacovigilance (DSPV) on epidemiologic analyses supporting background rates, safety surveillance, post-marketing commitments, and risk assessment.
• Provide strategic oversight and input into clinical plans, publications, and integrated evidence strategies.
• Partner with HEOR and Market Access leadership to generate fit-for-purpose RWE demonstrating clinical value, effectiveness, cost-effectiveness, and budget impact.
• Ensure RWE outputs meet global payer, HTA, and regulatory evidentiary expectations, anticipating evolving requirements.
• Serve as a primary functional representative in scientific advice meetings and evidence discussions with regulatory agencies and HTA bodies.
• Engage and influence external stakeholders including regulators, academic experts, data partners, industry consortia, and advisory boards.
• Represent the Epidemiology & RWE function in governance forums, internal and external scientific engagements.
• Oversee and ensure consistency, scientific integrity, and quality of all epidemiology and observational research programs.
• Contribute to regulatory submission planning, including data strategies, integrated summaries, and evidence positioning.
• Develop and maintain functional processes, SOPs, and compliance frameworks to support scalable and high-quality evidence generation.
• Serve as the escalation point for complex scientific, regulatory, or payer-facing evidence issues.
• Perform other duties as assigned.

Requirements

Typical Experience or Education:

• Master's Degree AND 12+ years of relevant experience OR
• PhD, PharmD, or MD in Epidemiology, Public Health, or a related field AND 10+ years of pharmaceutical or biotech experience in epidemiology and/or real-world evidence.
• Previous management experience.

Common Knowledge And Skills:

• Acts as a "trusted advisor" across the company and may be recognized as an external expert.
• Provides strategy, vision, and direction regarding issues that may have company-wide impact.
• Requires in-depth knowledge of the functional area, business strategies, and the company’s goals.
• Must be self-motivated and detail-oriented with the ability to quickly learn and think independently.
• Excellent leadership, coaching, and employee development skills.
• Ability to effectively lead a team with demonstrated proficiency in hiring, training, and supervision.
• Excellent interpersonal & communication skills with the ability to interact professionally and effectively with peers, management, and leadership both within and outside the company.
• Ability to work with a team of individuals to meet organizational goals.
• Possesses industry-leading knowledge pertaining to clinical and regulatory aspects of a pharmaceutical company.
• Evaluates key business/scientific challenges and completes complex, ambiguous initiatives having cross-functional impact.
• Ability to apply advanced analytical thought and judgment.
• Ability to work in a cross-functional team and a matrix environment.
• Excellent organizational and time management skills with the ability to work independently and coordinate workload under pressure to meet established deadlines.
• Excellent interpersonal skills and problem-solving capabilities.

Job Specific Knowledge And Skills:

• Demonstrated leadership of enterprise-level evidence strategies, complex cross-functional programs, and people leaders.
• Deep understanding of regulatory, HTA, payer, and market access evidence requirements.
• Strong communication, influence, and stakeholder management skills.

Pay

The annual base salary we reasonably expect to pay is $230,100.00-$314,000.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 35% of the earned base salary and eligibility to participate in our equity-based long-term incentive program.

Benefits

• Retirement savings plan (with company match).
• Paid vacation, holiday, and personal days.
• Paid caregiver/parental and medical leave.
• Health benefits to include medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans.