Sr. Director, Commercial Supply Chain

Position Summary

Reporting to the VP, Global Manufacturing & Supply Chain, the Sr. Director of Commercial Supply Chain will provide strategic and operational leadership for end-to-end supply chain planning across late phase clinical and commercial programs. This role is responsible for ensuring uninterrupted supply of small molecule drug substance, drug product and packaging & labeling through robust planning, inventory management, and cross-functional coordination.

Job Responsibilities

• Strategic Supply Chain Leadership & Planning

• Define and execute global supply chain strategies to support clinical development, commercialization, and lifecycle management.
• Lead end-to-end Sales & Operations Planning (S&OP) and Clinical Operations Planning (C&OP) processes.
• Ensure alignment of demand forecasts with manufacturing and supply capabilities.
• Provide strategic input into supply chain network design, long-term capacity planning, and budget development.

• Demand Planning, Forecasting & Supply Balancing

• Collaborate with Clinical Operations, Commercial, and CMC teams to develop accurate demand forecasts.
• Lead demand and supply balancing activities across all supply chain echelons.
• Establish processes to continuously refine forecasts and improve planning accuracy.
• Sure alignment of demand signals with production and procurement plans.

• Inventory Management & Optimization

• Define and manage inventory strategies across the global network.
• Establish operational and strategic safety stock levels to mitigate supply risk.
• Monitor inventory performance, including turns, expiry risk, and working capital.
• Drive optimization of inventory levels to balance service, cost, and risk.

• Launch Planning & Commercial Readiness

• Lead supply chain planning for product launches, including scenario planning and risk mitigation.
• Ensure readiness of supply chain systems, processes, and inventory to support successful launches.
• Partner with cross-functional teams to support regulatory milestones and market entry.

• Network Planning & Risk Management

• Lead long-range supply chain network planning to support growth and commercialization.
• Identify and mitigate supply risks through scenario planning, redundancy strategies, and contingency planning.
• Develop and maintain risk management frameworks across the supply chain.
• Support business continuity planning and supply resilience initiatives.

• Systems, Tools & Data Management

• Lead design, selection, and implementation of supply chain planning tools.
• Ensure effective master data management to support planning and execution.
• Support ERP system implementation and integration for new products and supply chains.
• Drive digital transformation and data-driven decision making in supply chain operations.

• Logistics, Distribution & Storage

• Oversee storage, shipping, and distribution strategies for clinical and commercial products.
• Ensure compliance with requirements for controlled room temperature (CRT) and cold chain products.
• Cook up logistics across global CDMOs, depots, and distribution partners.
• Optimize distribution networks to ensure timely and cost-effective delivery.

• Cross-Functional Leadership & Execution

• Partner closely with External Manufacturing, Quality, Regulatory, Clinical Operations, and Commercial teams.
• Serve as a key member of the Manufacturing & Supply Chain and Technical Operations teams.
• Drive continuous improvement initiatives across supply chain processes.
• Ensure alignment across stakeholders to support uninterrupted patient supply.

Qualifications

• B.S. in Supply Chain, Engineering, Chemistry, or related discipline required; MBA preferred.
• 15+ years of experience in supply chain management within the pharmaceutical or biotech industry.
• Deep expertise in small molecule manufacturing and oral solid dose (OSD) products/supply chains.
• Deep expertise in supply chain planning, S&OP/C&OP, and inventory management.
• Proven experience in launch planning and commercialization support.
• Experience with global outsourced supply chains and CDMO networks.
• Strong knowledge of GMP regulations, validation, CPV, and quality systems.
• Expertise in supply chain planning systems and ERP implementations.
• Experience with supply chain integration, production planning, and capacity management.
• Strong knowledge of logistics, distribution, and cold chain requirements.
• Demonstrated experience in risk management and supply chain resilience.
• Excellent leadership, communication, and cross-functional collaboration skills.
• Able to operate effectively in a fast-paced, matrixed, and virtual organization.
• Strategic thinker with strong execution and decision-making capabilities.
• Proven ability to build high-performing teams and operate in matrix environments.
• Strategic thinker with strong execution capabilities.
• Excellent communication and cross-functional influence.

Pay

The anticipated base pay range is $248,000-$305,000. The exact base pay offered for this role will depend on various factors, including but not limited to the candidate’s geography, qualifications, skills, and experience.

Benefits

• Medical, dental, and vision insurance
• 401(k) match
• Unlimited PTO
• A number of paid holidays including winter shutdown

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