Jobs · Research · California

Sr Associate Scientist, Process Development

Gilead Sciences · San Francisco Bay Area · 4 days ago
Research$127k–$164k/yrFull-time

Purification Development

Design, implement, and continuously improve automated, high-throughput purification assays, including miniaturized resin screening and binding studies.

Develop and maintain scalable, reproducible robotic workflows using liquid handling and automation platforms.

Translate traditional column scale purification concepts into low-mass, high-information screening formats that support rapid decision making.

Develop and apply mechanistic models (e.g., adsorption, binding kinetics, transport phenomena) to interpret purification data and guide experimental design and operating window definition.

Apply multivariate analysis, machine learning, and statistical modeling to analyze complex datasets, identify trends, and predict purification performance under varying conditions.

Process Development Impact

Enable early identification of process risks, sensitivities, and operating windows to support purification process design.

Inform resin selection, buffer strategies, and process parameters using data driven insights.

Contribute to platform and capability development that benefits multiple programs across the Gilead Biologics portfolio.

Collaboration & Communication

Partner closely with cross functional teams in Purification, Automation, Analytics, and Data Science.

Communicate results clearly through technical reports, presentations, and data visualizations tailored to diverse audiences.

Contribute to Gilead internal best practices, knowledge sharing, and long-term technology strategy within Purification Development.

Qualifications

  • B.S. with 5 years of industry experience in a relevant scientific discipline (e.g. chemical engineering, bioengineering, chemistry, or biochemistry)
  • OR M.S. with 3 years of industry experience in a relevant scientific discipline (e.g. chemical engineering, bioengineering, chemistry, or biochemistry)
  • Strong foundation in protein purification, chromatography mechanisms, and downstream process development
  • Hands on experience with laboratory automation and high-throughput robotics (e.g. Hamilton, Tecan, or similar platforms)
  • Experience designing and executing miniaturized purification, binding, or screening assays
  • Background in mechanistic modeling of purification or related physical/chemical processes
  • Demonstrated ability to independently design, analyze, and troubleshoot complex experimental systems
  • Excellent written and verbal communication skills, with a collaborative and team-oriented mindset

Preferred Qualifications

  • Experience applying machine learning, multivariate analysis, or advanced statistics to experimental datasets
  • Proficiency in Python, R, MATLAB, or similar tools for data analysis, modeling, and automation integration

Salary Range

$126,820.00 - $164,120.00

The salary range for this position is: $126,820.00 - $164,120.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary.

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