Site Manager, Clinical Trial Operations

About the role

The Clinical Trial Operations Site Manager will support and grow multiple research sites across Tennessee, Alabama, North Carolina, and South Carolina. This role is ideal for someone who enjoys being in the field, building strong site relationships, and helping establish operational excellence in a fast-growing organization.

Key Responsibilities

• Provide operational leadership and on-site support for multiple clinical research sites across the assigned region
• Serve as the primary operational resource for assigned sites, proactively identifying and removing barriers to successful study execution
• Coverage of vendor agreements and partnerships that support efficient site operations
• Support study startup activities including feasibility, site activation, staffing readiness, staff training, and sponsor/CRO coordination
• Monitor study performance metrics including enrollment, retention, protocol compliance, data quality, query resolution, and study timelines
• Identify operational challenges and implement scalable process improvements to enhance efficiency and site performance
• Partner with leadership to build and standardize operational processes, workflows, and best practices across the growing site network

Qualifications

• Bachelor’s degree in Life Sciences, Healthcare Administration, Business Administration, or a related field preferred
• 5+ years of clinical research experience required with recent hands-on site experience (CRC, Lead CRC, Site Manager, or similar) strongly preferred
• Strong knowledge of GCP, FDA regulations, ICH guidelines, and clinical trial operations
• Experience working with Sponsors, CROs, Principal Investigators, and clinical research sites
• Demonstrated ability to manage multiple priorities across multiple locations while maintaining strong attention to detail
• Excellent communication, organizational, relationship-building, and problem-solving skills
• Proficiency with CTMS, EDC systems, Microsoft Office, and other clinical research technology platforms
• Ability and willingness to travel regularly throughout Tennessee, Alabama, North Carolina, and South Carolina