Senior Vice President, Sales & Marketing

About the role

The Senior Vice President, Sales & Marketing will report to the Chief Commercial Officer and play a critical leadership role in preparing Cabaletta Bio for the anticipated launch of rese-cel in dermatomyositis. This individual will be responsible for building and leading the Sales and Marketing organization, developing commercial capabilities, and executing launch readiness activities in close partnership with the CCO and cross-functional stakeholders.

Responsibilities

• Partner with the Chief Commercial Officer to develop and execute the commercial strategy for rese-cel, including market development, customer engagement, brand strategy, and launch readiness activities.
• Lead commercialization planning and execution to ensure successful launch preparation and market adoption.
• Translate commercial strategy into actionable sales and marketing plans, objectives, and performance metrics.
• Provide customer, market, and competitive insights to inform commercial decision-making and launch planning.
• Support forecasting, business planning, and commercial analytics activities.
• Build, lead, and develop a high-performing Sales and Marketing organization capable of supporting a successful launch and long-term growth.
• Develop organizational structure, hiring plans, talent strategies, and capability-building programs for commercial functions.
• Establish performance expectations and foster a culture of accountability, collaboration, and execution excellence.
• Lead launch planning and execution for rese-cel, including field force design, deployment strategy, promotional planning, customer engagement, and treatment center activation.
• Partner with Market Access to support payer engagement strategies, reimbursement readiness, and site-of-care considerations.
• Collaborate with Operations, Manufacturing, and Patient Services teams to ensure commercial readiness for the unique logistical and operational requirements of cell therapy delivery.
• Help establish customer-facing processes supporting patient identification, treatment center engagement, scheduling, chain of identity, and chain of custody.
• Partner closely with Medical Affairs to ensure scientifically accurate and compliant promotional messaging and educational initiatives.
• Collaborate with IT to develop and implement commercial systems, CRM platforms, order management capabilities, and analytics tools required to support launch execution.
• Work closely with Regulatory, Legal, Compliance, and Quality partners to ensure all commercial activities meet applicable legal and regulatory requirements.
• Serve as a key member of the Commercial Leadership Team and contribute to broader company initiatives and strategic planning.
• Build and maintain strong relationships with key opinion leaders, treatment centers, advocacy organizations, and other critical stakeholders.
• Represent the company at industry, scientific, and commercial meetings as appropriate.
• Monitor market dynamics, competitive activities, and evolving customer needs to identify opportunities and risks.
• Develop and manage commercial budgets and resource plans in alignment with organizational priorities.
• Ensure effective and efficient deployment of commercial investments to achieve launch and business objectives.

Qualifications

• Bachelor's degree required; advanced degree (MBA, PharmD, MD, or other relevant graduate degree) preferred.
• Minimum 15 years of progressive commercial experience within biotechnology, biopharmaceuticals, or specialty pharmaceuticals.
• Significant commercial leadership experience with a demonstrated track record of building, scaling, and leading successful sales and marketing organizations.
• Experience supporting, leading, or executing a product launch in cell therapy, gene therapy, or another complex specialty therapeutic area.
• Deep understanding of cell therapy commercialization, including treatment center engagement, patient access, operational logistics, chain of identity, and chain of custody requirements.
• Demonstrated success partnering across Medical Affairs, Market Access, Operations, IT, Regulatory, and Compliance functions.
• Strong financial, analytical, and business planning capabilities.

Preferred Qualifications

• Direct commercialization and/or launch experience in CAR-T or other autologous cell therapies.
• Experience in rare disease, immunology, rheumatology, autoimmune disease, or other specialty therapeutic categories.
• Experience working in a clinical-stage or growth-stage biotechnology company preparing for its first commercial launch.