Senior Security Engineer

About the role

At Variant Bio, protecting the data entrusted to us by our partner communities is fundamental to our mission. We're seeking a Senior Security Engineer to build and monitor the systems that safeguard our products and infrastructure, along with the privacy of the people who work with us.

Key responsibilities

• Monitor, detect, and respond to threats across Variant Bio's products and AWS cloud infrastructure.
• Design and implement security tools and solutions as needs evolve.
• Perform regular policy review and compliance assessments.
• Develop security-focused code, libraries, and frameworks for use across engineering teams, and collaborate with security and product development teammates to solve complex challenges and raise the bar across the organization.

Qualifications

• Must have:
• B.S. or M.S. in Computer Science or related field, or equivalent experience.
• 8+ years designing and implementing security systems, tools, or frameworks.
• Strong experience with AWS security services, IAM, SSO, and Control Tower for multi-account governance, including administering cross-account and cross-region IAM permissions.
• Networking experience with knowledge of VPN and Zero Trust connectivity.
• Extensive knowledge of attacker tactics, techniques, and procedures.
• Proficiency in Python, Rust, or another programming language.
• Ability to rapidly prototype and iterate on security solutions.
• Nice to have:
• Knowledge of AI/ML security, including model pipelines, training data, and emerging threats such as prompt injection and data exfiltration.
• A track record of driving ISO 27001 or SOC 2 readiness.
• Background securing systems in a clinical, healthcare, or FDA-regulated environment.
• Familiarity with data handling regulations, including HIPAA and GDPR.
• Demonstrated ability to influence engineers building security products.
• Contributions to the security or privacy community (research, open source, presentations).

Compensation & Perks

At Variant Bio, we’re building something meaningful and we believe supporting our people is essential to that mission. We offer a thoughtful and competitive set of benefits designed to support your health, growth, and life outside of work.

• Competitive Compensation & Equity – Market-competitive salary with the opportunity to participate in company equity and share in our long-term success.
• Comprehensive Health Benefits – Variant Bio covers 100% of employee premiums for medical, dental, and vision insurance. Dependents may be added to the plan at an incremental cost.
• Flexible Time Off – Flexible paid time off and company holidays, with an emphasis on trust and personal responsibility.
• 401(k) Plan – Employer-sponsored retirement plan with company match.
• Professional Growth – Support for learning and development.
• Collaborative, Mission-Driven Culture – Work alongside a highly engaged, interdisciplinary team passionate about transforming human health through genetics.
• Early-Stage Impact – A chance to make a meaningful contribution at a growing biotech where your work has visible impact.

Anticipated annual base salary for this position is $160,000 - $210,000 plus up to 15% bonus and an options package, for total compensation of up $184,000 - $241,500 plus equity options. The annual salary range above is based on the responsibilities and qualifications listed above. Individual salary will depend on job-related knowledge, skills, and experience.