Jobs · Research · California

Senior Scientist, Target Discovery & Biology - Functional Genomics

BioSpace · South San Francisco, CA · 2 mo ago
ResearchFull-time

Key Responsibilities

  • Leverage functional genomics approaches across therapeutic areas to discover novel targets and address key biological questions
  • Lead, support and execute projects from inception through target identification, validation and mechanism-of-action studies
  • Foster a collaborative, creative, and scientifically rigorous team culture committed to delivering impact across Amgens pipeline

Basic Qualifications

  • Doctorate degree PhD OR PharmD OR MD [and relevant post-doc scientific experience in Target Discovery & Biology]
  • Masters degree and 3 years of relevant scientific experience in Target Discovery & Biology
  • Bachelors degree and 5 years of relevant scientific experience in Target Discovery & Biology

Preferred Qualifications

  • Strong experience in molecular biology and cell engineering
  • Experience in complex and co-culture in vitro models is a major plus
  • Experience in executing large scale, complex, and/or in vivo genetic screens (particularly CRISPR-based) and follow up validation studies
  • Track record of pushing the envelope on scale and technical feasibility is highly desirable
  • Familiarity with data-driven discovery approaches, including integration of genetic or multi-omics insights
  • Excellent organizational and communication skills, with the ability to drive cross-site collaboration in a matrixed research environment

What We Expect Of You

  • Strong experience in molecular biology and cell engineering
  • Experience in complex and co-culture in vitro models is a major plus
  • Experience in executing large scale, complex, and/or in vivo genetic screens (particularly CRISPR-based) and follow up validation studies
  • Track record of pushing the envelope on scale and technical feasibility is highly desirable
  • Familiarity with data-driven discovery approaches, including integration of genetic or multi-omics insights
  • Excellent organizational and communication skills, with the ability to drive cross-site collaboration in a matrixed research environment

What You Can Expect From Us

  • Award-winning time-off plans
  • Flexible work models where possible
  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives

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