Senior Scientist (Small Molecule, Synthetics)

Join Amgen’s mission of serving patients. At Amgen, our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With a focus on four therapeutic areas—Oncology, Inflammation, General Medicine, and Rare Disease—we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives.

About the role

In this vital role, you will serve as part of the Drug Product Team (DPT), providing creative functional area strategies, crafting and executing DOEs during the development of pivotal and commercial-ready programs. This Amgen leader will apply deep expertise in organic chemistry and their assemblies to develop innovative, fast-paced approaches as part of cross-functional teams. You will interface within the DPT department and with other Amgen functions, such as Drug Substance Technologies, Attribute Sciences, Quality Assurance, Regulatory Affairs, Supply Chain, Contract Manufacturing, Pharmacokinetics and Drug Metabolism, Clinical Development, and Biostatistics.

Responsibilities

• Design and execute experiments to support drug product development objectives.
• Summarize results in technical documents, regulatory filings, and presentations.
• Engage proactively and effectively with external industry groups, such as the IQ Consortium, and academic partners, such as university consortia.
• Provide technical expertise related to structure, reactivity, and physicochemical properties of materials (drug substance, excipients, etc.).

Requirements

• Doctorate degree (PhD) or PharmD or MD (with relevant post-doc where applicable) OR Master’s degree and 3 years of scientific related experience OR Bachelor’s degree and 5 years of scientific related experience.

Qualifications

• Ph.D. in a relevant scientific field, such as Organic Chemistry, Physical Chemistry, Chemical Engineering, Materials Science, or Pharmaceutical Sciences.
• Strong scientific background for the deep understanding of organic molecules and their assemblies.
• Profound scientific acumen with a focus on organic chemistry, Physical Chemistry, solid-state chemistry, and the physicochemical properties of small molecules.
• Industry experience: Prior work in the pharmaceutical sector, particularly with oral solid dosage forms.
• Technical proficiency: Familiarity with a wide array of characterization techniques, including but not limited to XRPD, DSC, TGA, and SEM.
• Patent process knowledge: Understanding of the patent application process and the legal framework governing patents is advantageous.
• Demonstrated understanding of scientific principles related to solid dosage forms.
• Manufacturing insights: Comprehensive knowledge of unit operations involved in producing oral solid dosage forms.
• Research leadership: Ability to design, conduct, and complete independent formulation research.
• Publication record: Demonstrated history of research dissemination through publications.
• Team collaboration: Proven track record of effective cross-functional team engagement.
• Writing excellence: Exceptional technical writing capabilities with meticulous attention to detail.
• A proactive, curious, and innovative mindset, with enthusiasm for applying digital solutions to scientific challenges.

Benefits

• A comprehensive employee benefits package, including:
  • A Retirement and Savings Plan with generous company contributions.
  • Group medical, dental, and vision coverage, life and disability insurance, and flexible spending accounts.
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan.
  • Stock-based long-term incentives.
  • Award-winning time-off plans.
  • Flexible work models where possible.

Pay

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.