Senior Scientist (Small Molecule, Synthetics)

About the role

Join Amgen’s Drug Product Team (DPT) as a Senior Scientist specializing in small molecule synthetics. In this role, you will provide creative functional area strategies and execute Design of Experiments (DOE) during the development of pivotal and commercial-ready programs. You will apply deep expertise in organic chemistry to develop innovative, fast-paced approaches within cross-functional teams, interfacing with departments such as Drug Substance Technologies, Attribute Sciences, Quality Assurance, Regulatory Affairs, Supply Chain, Contract Manufacturing, Pharmacokinetics and Drug Metabolism, Clinical Development, and Biostatistics.

Responsibilities

• Design and execute experiments to support drug product development objectives.
• Summarize results in technical documents, regulatory filings, and presentations.
• Engage proactively with external industry groups (e.g., IQ Consortium) and academic partners (e.g., university consortia).
• Provide technical expertise related to the structure, reactivity, and physicochemical properties of materials (drug substance, excipients, etc.).

Qualifications

Basic Qualifications

• Doctorate degree (PhD, PharmD, or MD) with relevant post-doc experience where applicable, or
• Master’s degree and 3 years of scientific experience, or
• Bachelor’s degree and 5 years of scientific experience.

Preferred Qualifications

• Ph.D. in Organic Chemistry, Physical Chemistry, Chemical Engineering, Materials Science, or Pharmaceutical Sciences.
• Strong scientific background in organic molecules and their assemblies.
• Profound scientific acumen in organic chemistry, physical chemistry, solid-state chemistry, and physicochemical properties of small molecules.
• Industry experience in the pharmaceutical sector, particularly with oral solid dosage forms.
• Technical proficiency with characterization techniques (e.g., XRPD, DSC, TGA, SEM).
• Knowledge of the patent application process and legal frameworks governing patents.
• Demonstrated understanding of scientific principles related to solid dosage forms.
• Comprehensive knowledge of unit operations for producing oral solid dosage forms.
• Ability to design, conduct, and complete independent formulation research.
• Publication record demonstrating research dissemination.
• Proven track record of effective cross-functional team collaboration.
• Exceptional technical writing skills with meticulous attention to detail.
• Proactive, curious, and innovative mindset with enthusiasm for applying digital solutions to scientific challenges.

Benefits

Amgen offers a Total Rewards Plan, based on eligibility, including:

• A comprehensive employee benefits package (Retirement and Savings Plan with generous company contributions, group medical, dental, and vision coverage, life and disability insurance, and flexible spending accounts).
• A discretionary annual bonus program (or sales-based incentive plan for field sales representatives).
• Stock-based long-term incentives.
• Award-winning time-off plans.
• Flexible work models where possible.

Pay

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted on the careers site. Actual salary will vary based on relevant skills, experience, and qualifications.

Amgen fosters an inclusive environment and is an Equal Opportunity employer. We consider all qualified applicants without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. Individuals with disabilities may request reasonable accommodation to participate in the job application or interview process.