Jobs · Analyst · Pennsylvania

Senior Scientist Pharmacokinetics

Merck · Lower Gwynedd, PA · 1 mo ago
Analyst$117k–$184k/yrFull-time
We need to output HTML fragment with sections only if content present. Must use

for headings: About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. We must not repeat job title. Must not include Job ID etc. Must preserve all substantive info, remove boilerplate (cookie/navigation/legal/EEO/equal-opportunity/scam-warning, duplicated lines, application instructions). Also must not include sections with filler like "commensurate with experience". We have salary range info, so Pay section should be included. Benefits info present, so Benefits section. Schedule? Not mentioned; no schedule info, so omit Schedule. About the role: we have description paragraph at start: "We are seeking a highly motivated Senior Scientist...". That's about the role. Could be placed under About the role. Responsibilities: list bullet points. Qualifications: required qualifications. Preferred qualifications maybe under Qualifications? The instruction: Use headings for Qualifications and Skills separate. So Qualifications heading for required qualifications? Skills heading for required skills and preferred skills? The posting lists "Required Skills" and "Preferred Skills". Also "Preferred Experience". We could put required skills under Skills heading, and maybe preferred skills also under Skills? But we need to preserve all substantive info. Could separate Required Skills and Preferred Skills under Skills heading with sub-lists? Not required to have subheadings; just list items. Could combine required and preferred skills into one list? Might lose distinction but still preserve info. Better to keep two sub-lists with headings? But we cannot add extra headings beyond the allowed ones? The instruction: use

for section headings (e.g. About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule). It doesn't forbid other headings, but says "use

for section headings (e.g ...)". Likely they expect only those headings. We could put required skills under Skills heading, and preferred skills also under Skills heading but maybe label with text? Could add a

before list indicating "Required skills:" then list, then another

for "Preferred skills:" then list. That preserves info. Requirements heading: The posting has a section "Requirements" after Preferred Skills? Actually after Preferred Skills there is "Required Skills Cytometry, GraphPad Prism, Immunoassays, Immunology Research, Ligand Binding Assay, Pharmacokinetics, Pharmacology, Sample Preparations, Scientific Presentations, Scientific Research, Scientific Writing, Technical Reviews, Vaccine Development Preferred Skills Current Employees apply HERE Current Contingent Workers apply HERE US And Puerto Rico Residents Only ..." Then later "Requirements As an Equal Employment Opportunity Employer..." That's EEO boilerplate which we must remove. So the Requirements heading content is mostly EEO boilerplate which we should drop. So we may omit Requirements section because after removing boilerplate there is no substantive content. However there is also "Requirements" earlier? Actually the posting includes a "Requirements" heading after the Preferred Skills block, but it's just EEO statement. So we should omit Requirements section. Qualifications: we have Required qualifications (Ph.D etc) and Preferred Experience. So we can put under Qualifications heading both required and preferred experience. Could separate with paragraphs. Skills: we have Required Skills list and Preferred Skills list. We'll include both. Benefits: we have description of benefits. Pay: salary range. Schedule: none. About the role: introductory paragraph. Responsibilities: bullet list. Now we need to output HTML fragment only, no /. Use

for each section heading. Use
  • for lists. Use

    for prose. We must not include duplicated lines. Ensure we preserve all substantive info: responsibilities list, qualifications, preferred experience, required skills, preferred skills, benefits description, salary range. Let's extract details. About the role paragraph: "We are seeking a highly motivated Senior Scientist to join the Exploratory Vaccines and Regulated Robotics team within the Department of Regulated Bioanalytics at our company. Our team is dedicated to developing, validating, and implementing assays used to evaluate vaccine and biologic candidates in clinical studies. This is an exciting opportunity to lead hands-on development, optimization, qualification, and clinical-study implementation of immunology-based assays, with an emphasis on cellular assays that assess functional T-cell and B-cell responses, and innate immune activation. Join us in applying laboratory science, automation, and data-driven decision-making to strengthen bioanalytical support for vaccine and biologics programs." That's the about. Responsibilities bullet list (as given): - Lead assay lifecycle activities for cell-based immunoassays, including design, execution, optimization, qualification, implementation, troubleshooting, documentation, and transfer readiness for preclinical and clinical samples. - Develop and apply cellular immunology methods, including intracellular cytokine staining, ELISpot/FluoroSpot, cytokine profiling, and related functional assays to characterize immune responses. - Support flow cytometry instrument readiness by performing calibrations, routine maintenance, troubleshooting, and coordination with vendors or operations teams for service and repair. - Author and review SOPs, test methods, qualification documents, technical reports, and scientific presentations; communicate assay strategy, data interpretation, technical risks, limitations, and recommendations to internal stakeholders, cross-functional teams, and external scientific audiences. - Apply laboratory experimentation, data analytics, automation, robotic liquid handling, and risk-based troubleshooting to improve assay performance, workflow efficiency, data quality, and overall bioanalytical capability. - Serve as an internal subject matter expert by providing scientific rationale, technical guidance, training, and mentoring to colleagues, junior scientists, and contractors. - Work effectively in a regulated GxP environment by maintaining accurate, contemporaneous, and complete documentation; supporting data integrity; and ensuring assay activities are conducted in accordance with applicable SOPs, test methods, and regulatory expectations. Qualifications: Required: "Ph.D. in immunology, cell biology, biology, bioengineering, or a related scientific discipline; or M.S. with 2+ years of relevant industry experience; or B.S. with 5+ years of relevant industry experience." Also: "Ability to work safely with viruses, bacteria, and potentially infectious human and animal samples under BSL-2 laboratory practices." "Experience working in, or strong understanding of, regulated bioanalytical workflows, GxP documentation practices, assay development, qualification/validation expectations, and data integrity principles." "Strong scientific judgment, experimental design, and troubleshooting skills, with the ability to independently identify root causes, assess technical risk, and recommend scientifically sound next steps." "Strong interpersonal, verbal, and written communication skills, including the ability to clearly communicate assay strategy, technical risks, data interpretation, and recommendations to scientific and cross-functional stakeholders." "Strong attention to detail, organizational skills, and ability to manage multiple studies, assay development activities, and documentation deliverables simultaneously." "Relevant experience in immunology, cell-based assay development, or regulated bioanalytical assay development." Preferred Experience: list: - Experience with human PBMC isolation, cryopreservation, thawing, culture, and maintenance of primary immune cells and/or relevant cell lines. - Broad experience assessing immune cell function using multiparameter flow cytometry, intracellular cytokine staining, T-cell and B-cell ELISpot/FluoroSpot, multiplex cytokine platforms, and related cellular immunology methods. - Hands-on experience developing, optimizing, and analyzing multicolor flow cytometry panels, including gating strategy development, compensation, controls, and interpretation of complex datasets. - Experience with liquid handlers, automated sample preparation workflows, data analytics, and other automation or digital tools used to improve assay consistency, throughput, data quality, and process robustness. - Working knowledge of standard data analysis and visualization tools such as FlowJo, GraphPad Prism, Microsoft Excel, PowerPoint, and related scientific software. Skills: Required Skills list: "Cytometry, GraphPad Prism, Immunoassays, Immunology Research, Ligand Binding Assay, Pharmacokinetics, Pharmacology, Sample Preparations, Scientific Presentations, Scientific Research, Scientific Writing, Technical Reviews, Vaccine Development" Preferred Skills: "Current Employees apply HERE Current Contingent Workers apply HERE US And Puerto Rico Residents Only" Actually that seems like application instructions not skills. Wait the posting had "Preferred Skills Current Employees apply HERE Current Contingent Workers apply HERE US And Puerto Rico Residents Only". That seems misplaced; maybe it's part of application instructions. Actually after Preferred Skills they list "Current Employees apply HERE Current Contingent Workers apply HERE US And Puerto Rico Residents Only". That's not skills. Then later they have "Our company is committed to inclusion..." etc. So the Preferred Skills list might be missing; maybe they omitted. The text shows "Preferred Skills Current Employees apply HERE Current Contingent Workers apply HERE US And Puerto Rico Residents Only". That seems like a mistake; we should treat that as not skills. So we have only Required Skills list. There's no explicit Preferred Skills list besides that nonsense. We'll ignore that line as boilerplate/application instructions. Thus Skills section will contain required skills list. Benefits: "We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits." Pay: "The salary range for this role is $117,000.00 - $184,200.00 This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs. The successful candidate will be eligible for annual bonus and long-term incentive, if applicable." We should preserve all that info. Could be a paragraph. Schedule: none. Now produce HTML. Structure:

    About the role

    ...

    Responsibilities

    • ...
    • ...

    Qualifications

    Required: ...

    Ability to work safely ...

    ... etc. Could combine into multiple

    or

      . Since it's a list of qualifications, better to use
        . But the instruction: Use
        • for any list of duties/requirements/benefits. Qualifications is a list of requirements, so use
            . We'll put each qualification as
          • . Preferred experience also could be under Qualifications as separate
          • maybe with note "Preferred". We'll include them as
          • with text. Similarly Skills: list of required skills ->
            • each skill? The list is comma-separated; we could split into items. Better to keep as a single
            • with the comma-separated list? The instruction: use
              • for any list of duties/requirements/benefits. Skills is a list, so we should split. We'll split by commas. Benefits: list of benefits ->
                • . Pay: paragraph. Now ensure we don't include boilerplate like EEO, accommodation, application instructions, etc. Let's craft. About the role paragraph: exactly as given. Responsibilities: list each bullet. Qualifications: list items: - Ph.D. in immunology, cell biology, biology, bioengineering, or a related scientific discipline; or M.S. with 2+ years of relevant industry experience; or B.S. with 5+ years of relevant industry experience. - Ability to work safely with viruses, bacteria, and potentially infectious human and animal samples under BSL-2 laboratory practices. - Experience working in, or strong understanding of, regulated bioanalytical workflows, GxP documentation practices, assay development, qualification/validation expectations, and data integrity principles. - Strong scientific judgment, experimental design, and troubleshooting skills, with the ability to independently identify root causes, assess technical risk, and recommend scientifically sound next steps. - Strong interpersonal, verbal, and written communication skills, including

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