Senior Scientist, NHP Study Lead / Analyst

About the role

Stylus Medicine is developing transformative in vivo genetic medicines to unlock cures. Stylus combines engineered recombinases with non-viral delivery to specifically encode therapeutics. The company’s approach is versatile and modular, with potential therapeutic application across oncology, autoimmune, genetic diseases, and beyond.

Key Responsibilities & Accountabilities

• Design NHP study protocols and lead CRO communication
• Analyze, interpret, and communicate NHP study data, including flow cytometry analysis, cytokine analysis and other ex vivo readouts, to inform project direction and decision-making
• Evaluate data for consistency and follow-up as needed, working closely with CROs to optimize study protocols
• Investigate and interpret biological findings from NHP studies
• Manage NHP study test article generation and transfer in collaboration with internal cross-functional teams
• Conduct experiments to optimize protocols for CRO transfer or investigate biological findings
• Generate and manage study documentation, including protocols and study reports
• Effectively communicate findings to internal teams
• Maintain detailed and accurate laboratory records in compliance with data integrity and documentation standards
• Limited travel may be required

Qualifications & Skills

• PhD in Pharmacology, Immunology, Immuno-oncology, or a related field with 4-6 years of relevant industry or academic experience, or a Master's degree with 8+ years of experience
• Demonstrated experience with ex vivo analytical techniques, such as flow cytometry, cytokine analysis, and ddPCR
• Demonstrated ability to design, execute, interpret, and troubleshoot immunology-related in vivo studies and to coordinate the activities of multiple study contributors
• Experience coordinating with animal vendors, CROs or external collaborators
• Prior experience with NHP studies is preferred
• Experience in designing experiments to address PK/PD/biodistribution/tox relationships is a plus
• Experience with LNP or CART delivery technologies and genetic medicine platforms is a plus
• Experience with T cell or PBMC isolation and handling from peripheral blood, engineering, and downstream immunological or molecular assays
• Demonstrated ability to work independently in a laboratory setting, learn new techniques, multitask effectively, and maintain meticulous records
• Demonstrated proficiency in documenting and maintaining an organized lab notebook, lab inventory, and experimental results
• Excellent organizational and communication skills, with a team-first mindset and the ability to convey technical information
• Analytical thinker with the ability to distill complex data into clear, actionable insights

Pay Range

$160,000 - $175,000