Senior Scientist, Immunology & Inflammation

About the role

This individual will have the opportunity to support a broad pipeline in allergic and inflammatory diseases by validating targets, assessing the efficacy of therapeutic candidate molecules in vitro and in vivo, and interrogating mechanisms of pathology that inform therapeutic strategies.

Responsibilities

• Contributes to project advancement by developing new methods and technologies.
• Troubleshoots methodological and technical issues, interprets experimental data and literature, and communicates results to supervisor, department, or project team.
• Executes experiments based on projects/protocols provided and works towards independently developing project.
• Collaborates and communicates efficiently with team members to coordinate complex in vivo experiments, and with other departments to facilitate cross-functional efforts.
• Experience with proper handling and care of mice, general surgical techniques and the collection of blood and tissue samples.
• Develops and optimizes relevant disease mouse models and the subsequent analysis of associated disease-related pathologies by flow cytometry, histology and ELISA.
• Develops and executes cell-based assays to screen candidate antibodies for various research programs. Performs ELISAs and or MSDs to measure cytokine levels and determine antigen binding for various research programs.
• Contributes to lab and equipment maintenance and orders supplies/reagents to help create a safe, effective and efficient working environment.

Requirements

• Ph.D + 0-2+ years experience.
• Minimum of 5-8 years of relevant research experience in immunology.
• Extensive experience with multi-parameter flow cytometry, panel design and data analysis.
• Knowledge of allergic and inflammatory diseases, with emphasis in skin and/or lung biology.
• Preferred experience developing and optimizing primary cell assays used to characterize cytokine and immunoreceptor pathways and screen antibody candidates.
• Must have a record of high-quality publications in scientific literature.
• Effective verbal communication and written skills.

Qualifications

• Ph.D in Biology, Immunology, or Cellular and Molecular Biology preferred but not required.
• Basic computer literacy and experience collecting and analyzing biological data on the computer.
• Experience with GraphPad PRISM, Softmax Pro, FlowJo analysis, HALO, DIVA software.
• Strong communication skills.

Benefits

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit here.

Pay

$109,900.00 - $179,300.00 annually

Schedule

Onsite