Senior Scientist II, Rheumatology
AbbVie · Cambridge, MA · 1 mo ago
AnalystFull-time
About the role
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.
Responsibilities
- Serve as a functional representative responsible for setting Rheumatology strategy for pipeline programs and contributing to target evaluation and model development.
- Drive in vitro and in vivo pharmacology for drug candidates, including establishing PK/PD relationships, developing, and optimizing screening assays, designing and executing mechanism-of-action studies, and evaluating candidate efficacy.
- Develop acute and/or chronic murine models of inflammation to support preclinical development of candidates for rheumatological and other autoimmune diseases.
- Apply immunological techniques such as flow cytometry, PCR/gene expression analysis, protein and cytokine quantification, histopathology, and other relevant functional readouts.
- Design experiments, analyze data, and present findings at AbbVie scientific forums and external conferences.
- Author and review technical reports, protocols, and other key scientific documents.
- Adhere to corporate standards related to code of conduct, documentation, safety, proper handling of materials, and humane treatment of laboratory animals.
Qualifications
- Bachelor’s Degree with 12 years of experience, Master’s Degree with 10 years of experience, PhD with 4 years of experience.
- Proven