Jobs · Analyst · Massachusetts

Senior Scientist, II Computational Neurobiology

BioSpace · Cambridge, MA · Today
AnalystFull-time
Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us atwww.abbvie.com. Follow @abbvie onLinkedIn,Facebook,Instagram,XandYouTube. Overview Job Description We are seeking an experienced and highly motivated neuroscientist with strong experimental and quantitative analysis expertise to join our Discovery Psychiatry team. The successful candidate will develop and apply data analysis workflows, including machine learning approaches where appropriate, to identify in vitro functional biomarkers that predict neural circuit modulation and behavioral outcomes in vivo. The ideal candidate will have hands-on experience in electrophysiology and/or other neuronal activity assays, along with the ability to work with multimodal datasets and extract biologically meaningful insights. This interdisciplinary role is an exciting opportunity to help build and standardize cross-scale translational frameworks that support target validation and compound profiling efforts in a dynamic, collaborative drug discovery environment. Key Responsibilities Design and execute hiPSC-based neuronal activity assays to support target validation and compound profiling efforts within psychiatryContribute to the development and implementation of computational analysis workflows that streamline interpretation of complex multimodal datasetsIntegrate data across assays and scales using quantitative and machine learning-based approaches to generate predictive frameworks that enable identification of translationally relevant functional signaturesEnsure alignment of assay development and data analysis efforts with broader cross-functional program team goalsPresent findings to internal teams to support strategic decision-making in psychiatry drug discoveryProvide scientific guidance and mentoring to junior scientists and research associates Qualifications Bachelors Degree or equivalent education and typically 12 years of experience, Masters Degree or equivalent education and typically 10 years of experience, PhD and typically 4 years of experience in neuroscience, computational biology, bioengineering, or a related fieldDemonstrated experience analyzing complex biological or neurophysiology datasets using quantitative and/or machine learning approachesStrong understanding of data analysis workflows and statistical methods applied to biological dataHands-on experience in the design and execution of in vitro assays related to synaptic and circuit functionExperience working with electrophysiology and/or other neuronal functional readoutsStrong ability to work in cross-functional teams and effectively communicate scientific findings to both technical and non-technical audiences Desired Qualifications Previous industry experience within early discovery neuroscienceExperience building translational frameworks or predictive scoring approaches for functional biology dataFamiliarity with hiPSC-derived neuronal modelsExperience working with multimodal datasets and integrating data across experimental platforms Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemayultimatelypaymore or less than the posted range. This range may bemodifiedin thefuture.We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees.This job is eligible toparticipatein our long-term incentiveprograms. Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employeeremainsin the Company's sole andabsolutediscretion unless and until paid andmay bemodifiedat the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visithttps://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html

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