Senior Scientist, Biologics Purification II
BioSpace · North Chicago, IL · Today
AnalystFull-time
About the role
Join AbbVie's Biologics Discovery Sciences group and make a tangible impact in advancing innovative biologic therapies. As a scientist specializing in Biologics Purification, you will play a pivotal role in driving drug discovery, collaborating within a dynamic team dedicated to supporting transformative science that improves patient lives worldwide.
Responsibilities
- Lead small-scale (
- Design and execute advanced chromatography techniques and robust bioprocess development strategies to address production impurities and liabilities to deliver high quality biologics to therapeutic areas
- Apply Design of Experiments (DOE) with high throughput automation to optimize chromatography conditions for enhanced separation and resolution of complex protein mixtures
- Leverage AI and programming expertise to design and build data capture workflows and data warehousing infrastructure that supports machine learning development
- Collaborate with multidisciplinary teams, translating molecular insights into functional results
- Present findings clearly to diverse audiences and document results with rigor
Requirements
- Deep proficiency in bioprocessing, column chromatography, and biotherapeutics manufacturing
- Experience operating high throughput automated liquid handling systems for chromatography applications (i.e. plate-based screening, robocolumns)
- Experience designing and executing DOE studies with successful application to protein production scale-up
- Experience with chromatography instrumentation and software (i.e. Unicorn)
- Experience developing bioinformatics tools and APIs for real-time data acquisition, extraction, and storage in LIMS environments
- Familiarity with programming languages (i.e. Python) and AI/ML tools
Qualifications
- BS, MS, or PhD in Bioinformatics, Biophysics, Chemical Engineering, or related field with typically 12+ years (BS), 10+ years (MS), or 4+ years (PhD) of experience
- Strong understanding of molecular and post-translational attributes of biologics
- Exceptional analytical, communication, and presentation skills
- Collaborative spirit and dedication to scientific excellence
Skills
- Programming languages (i.e. Python)
- AI/ML tools
Benefits
- Paid time off (vacation, holidays, sick)
- Medical/dental/vision insurance
- 401(k)
Pay
Compensation range is determined based on job grade and may be modified in the future. This job is eligible to participate in long-term incentive programs.
Schedule
Full-time