Senior Scientist - Assay Development

About the role

The Assay Development Team at Guardant Health is seeking a highly motivated scientist to develop novel technologies for cancer detection and profiling in a regulated environment.

Responsibilities

• Develop, test, validate, and improve NGS-based automated assays for oncology and cancer screening diagnostics.
• Explore and implement new technologies to drive assay innovation and workflow optimization.
• Integrate analytical tools and experimental design to evaluate performance in a high throughput sequencing sample preparation and specimen handling workflow.
• Collaborate across teams to solve development challenges, improve existing NGS workstreams, and propose/implement solutions.
• Operate molecular biology laboratory equipment, including automated liquid handlers, quantitation instruments, thermal cyclers, and NGS instruments.
• Present data, write technical reports and protocols, and communicate findings effectively to both technical and non-technical audiences.
• Train and support junior team members.
• Demonstrate strong commitment to delivering results in a fast-paced, dynamic environment at Guardant Health.

Qualifications

• PhD in Molecular Biology, Genomics, Biochemistry or related field, or equivalent work experience.
• A minimum of 5-8 years of industry experience developing and validating diagnostic assays.
• A strong foundation in molecular biology techniques including sample preparation for NGS and other molecular biology workflows.
• Experience developing assays optimized for implementation on automated liquid handling platforms.
• Quantitative/analytical mindset - ability to segment complex problems into fundamental parts/basic principles, develop models and experimental tests for those models, and synthesize results into actionable solutions.
• Demonstrated ability to organize, document and communicate scientific data.
• Consummate team player: demonstrated ability to thrive in an environment where numerous contributions are required to accomplish complex goals.
• Enjoy working independently and collaboratively in a fast-paced environment and are able to adapt to changing priorities.
• Curiosity, drive, and sense of humor.

Preferred Qualifications

• Experience developing products under design control.
• Familiarity with oncology or cancer biology AI.
• Data science and statistical analysis tools in Python and/or R.

Benefits

Guardant Health offers a competitive benefits package that includes:

• Health insurance
• Retirement savings plan
• Flexible spending accounts
• Employee assistance program
• Generous paid time off

Schedule

This role is currently available as a hybrid position, with a mix of remote and in-office work. Employees are required to be onsite on Mondays, Tuesdays, and Thursdays, and can work remotely on Fridays.

Pay

The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate's compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need.

• Primary Location: Palo Alto, CA - $138,400 - $190,300
• Other US Location(s): - $117,640 - $161,755
• If the role is performed in Colorado, the pay range for this job is: $124,560 - $171,270