Senior Safety Scientist

Responsibilities

• Proactive medical safety surveillance of ongoing clinical trials for identification and management of safety
• Prepare and present safety data summaries to internal and external stakeholders
• Risk management activities include, but are not limited to medical review of ICSRs, routine review of safety data and pertinent scientific literature articles
• Acquire and contribute knowledge of relevant drug class and/or competitor safety issues
• Identify potential clinical safety issues and recommend appropriate risk mitigation measures
• Perform safety review of clinical protocols, Investigator's Brochure (IB), informed consent form (ICF) and other related documents to ensure alignment with the safety strategy and ensure the appropriateness of risk management strategies and risk communication
• Conducts signal detection and evaluation activities for assigned products for the continuous benefit-risk evaluation throughout the product lifecycle and contributes/leads preparation for escalation to safety governance committees
• Supports implementation of decisions from the signal evaluation process, including updates to core safety information, Investigator’s Brochure and other key safety documents and deliverables
• Contributes to input related to regulatory filings, New Drug Applications [NDAs], Biologics License Applications [BLAs]), and responses to safety queries from third parties, such as regulatory agencies
• Establish and maintain collaborative working relationships with all key stakeholders (study team members, CROs, investigators, study sites, vendors, committees, etc.)

Requirements

• A relevant postgraduate qualification (e.g., MD, PharmD, PHD/MSc in a Life sciences discipline, or other post-graduate health professional qualifications)
• 3 or more years of drug development experience in the pharmaceutical or related industry with at least 1 year in drug safety

Qualifications

• Broad understanding of the scientific aspects of safety, PV (including GVP, GCP), and clinical/patient risk management and safety operations
• Demonstrated ability to lead and influence, with and without authority, in a fast-paced environment
• Strong presentation skills, effective at summarizing and presenting the key considerations and decision points
• Thrives in a collaborative team setting and is driven by a desire to deploy innovative approaches and technologies in a high-energy environment
• Detail-oriented with ability prioritize tasks and function independently as appropriate
• Excellent written and verbal communication skills