Senior Research Technologist - Lucas-McAllister Lab

Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans to take care of you and your family, now and in the future. With continuing education and advancement opportunities, you can build a long, successful career with Mayo Clinic.

About the Role

This is an exciting opportunity for an energetic, ambitious, and creative individual to help shape the future of a discovery-oriented biomedical research laboratory. The primary research focus of the lab centers on the interaction of cancer with the immune system. The lab is jointly directed by senior Principal Investigators:

• Dr. Peter Lucas - Vice Chair for Research, Department of Laboratory Medicine and Pathology
• Dr. Linda McAllister - Enterprise Deputy Director, Pediatric Cancer Programs, Mayo Clinic Comprehensive Cancer Center

The successful candidate will work closely with our group, which includes a Principal Research Technologist, a Senior Program Coordinator Administrative Leader, Senior Research Scientists, Post-Doctoral fellows, and PhD Student Trainees.

Responsibilities

• Support lab member projects via method development, conduction of experiments, data analysis, and interpretation.
• Design and complete experiments geared toward research objectives of the lab.
• Assist in routine laboratory operations including ordering, regulatory documentation/compliance (chemical safety, biosafety, IACUC, and IRBs), personnel training, equipment/reagent management, and maintenance.
• Demonstrate strong organizational and record-keeping skills, as well as the ability to accurately collect, store, and interpret research data.
• Contribute to manuscript and grant writing.
• Present at research laboratory meetings.
• Assist in the design of experiments and protocols.
• Execute experimental studies in support of lab goals.
• Perform experiments according to established procedures and under the direction of senior lab personnel.
• Maintain detailed logs of experimental procedures.
• Train lab personnel in lab techniques.
• Maintain equipment and supplies.
• Assist in the selection of instrumentation and computer software/hardware.
• Collect, document, and analyze data.
• Present at lab meetings and report difficulties in experimentation and data collection.
• Follow through with protocol modifications and troubleshoot problems using established or novel experimental procedures.
• Communicate effectively during team meetings about research design and results interpretation.
• Maintain inventory of supplies, chemicals, and animals in a written or electronic format.
• Provide training on the use of instrumentation and methods.
• Maintain governmental laboratory regulations and standards (e.g., IRB, IACUC, OSHA, Biosafety).
• Contribute to IACUC or IRB protocols.
• Interact and negotiate with supply and equipment vendors.
• Prepare graphs, tables, and figures for grants and manuscripts.
• Interpret results and report them to investigators.
• Strive to improve knowledge in the appropriate field of research investigation.
• Attend lectures, seminars, and journal clubs to increase knowledge base.
• Read literature to gain knowledge relevant to current work assignments.

Qualifications

• Requires a bachelor's degree in biology, chemistry, or other relevant science.
• Preference for candidates with 4 to 6 years of relevant research laboratory experience.
• Must exhibit a solid understanding of lab techniques, equipment, and safety.
• Must have the ability to organize and carry out laboratory techniques independently and in a team setting.
• Must be able to work with a variety of people at all levels both within and outside of the institution.
• Experience with basic data analysis is required.
• Skills in bioinformatics considered a plus.
• Demonstrated writing skills required.

Note: Visa sponsorship is not available for this position. Must be a U.S. citizen, permanent resident, refugee, or asylee.

Skills

• Cell Culture and Viral Techniques: Mammalian cell culture, transient transfection, lentiviral/retroviral production, and stable cell line generation.
• Protein Analysis: Western blotting, ELISA, immunohistochemistry (IHC), confocal microscopy.
• Molecular Biology and DNA Technologies: qPCR, DNA/RNA preparation, molecular cloning, and plasmid preparation.
• Flow Cytometry: Sample preparation, staining, and basic data acquisition/analysis.
• Animal Work: Mouse handling, murine tumor modeling, intraperitoneal (IP) injection, and subcutaneous injection.

Pay

$67,454.40 - $101,212.80 / year; Education, experience, and tenure may be considered along with internal equity when job offers are extended.

Benefits

• Medical: Multiple plan options.
• Dental: Delta Dental or reimbursement account for flexible coverage.
• Vision: Affordable plan with a national network.
• Pre-Tax Savings: HSA and FSAs for eligible expenses.
• Retirement: Competitive retirement package to secure your future.

Schedule

• Full Time
• Hours/Pay Period: 80
• Schedule Details: Normal business hours M-F; Flexible hours as needed.
• Weekend Schedule: Rarely; Flexible hours if needed.