Senior Research Specialist

This role supports the Meharry Center for Genome Research (MCGR) and Together for CHANGE (T4C) GREAT Health Study by performing hands-on processing of human biological specimens (blood, saliva, buccal samples) and ensuring accurate, compliant handling of all derived materials.

Responsibilities

• Perform wet-lab experiments for processing human blood, saliva, and buccal samples, including:
  • DNA extraction
  • RNA extraction
  • Plasma isolation
  • Serum isolation
• Work closely with project leadership and the lead scientist to uphold quality, safety, and workflow efficiency.
• Prepare, label, and track all samples according to established protocols.
• Store processed and unprocessed samples at appropriate subzero temperatures (−20°C, −80°C, liquid nitrogen) following institutional biosafety requirements and maintain a biorepository of all human biospecimens.
• Enter and maintain accurate sample metadata in the Laboratory Information Management System (LIMS) to ensure traceability and compliance.
• Follow all institutional biosafety guidelines for handling human biological materials.
• Maintain cleanliness, organization, and readiness of the sample processing workspace.
• Communicate promptly with project leads regarding sample status, workflow needs, and any deviations or issues.
• Support continuous improvement of sample handling workflows and documentation.
• Manage general laboratory operations, including inventory management and supply ordering.
• Prepare and operate laboratory equipment such as liquid handlers, pipette automation systems, spectrophotometers, barcode scanner systems linked to LIMS, and the KingFisher APEX-DX for automated DNA extraction.
• Prepare reagents and clean laboratory equipment as needed.

Requirements

• Bachelor’s or master’s degree in biology, biochemistry, molecular biology, or a related field, with 3–5 years of basic science research laboratory experience.
• At least 1 year of experience in biorepository and laboratory management.
• Prior experience working with human samples, or willingness to learn and work in a clinical research laboratory environment involving human specimens.
• Familiarity with nucleic acid extraction techniques (manual or automated).
• Strong attention to detail, accuracy in record-keeping, and adherence to protocols.
• Ability to work independently under minimal supervision while collaborating effectively with the project team, including clinical coordinators and other clinical staff.
• Commitment to maintaining confidentiality, safety, lab orders & supplies, and regulatory compliance.

Preferred Qualifications

• PhD in biological sciences or related fields.
• Basic science wet lab experience in molecular biology or a related field of research.
• Experience with LIMS or digital sample-tracking systems.

This position is funded through a grant and is contingent upon the availability of grant funding. Employment is expected to continue for the duration of the grant period, subject to satisfactory performance and continued availability of funding.