Senior Research Associate (Stem Cell)

This role is based in Cambridge, MA.

About the role

Support the development of innovative cell-based therapies through hands-on laboratory experimentation and data analysis in stem cell research, genetic engineering studies, and translational biology programs.

Responsibilities

• Perform routine culture, expansion, maintenance, and differentiation of human stem cells and other mammalian cell lines.
• Support research initiatives involving cellular engineering, gene modification, and evaluation of cellular function in both laboratory and preclinical settings.
• Monitor cell health, growth characteristics, sterility, and experimental quality while maintaining detailed laboratory records.
• Carry out molecular and cellular biology techniques, including nucleic acid extraction, cDNA preparation, gene expression analysis, and protein-based assays.
• Conduct experiments using technologies such as flow cytometry, quantitative PCR, digital PCR, ELISA, immunofluorescence, and related analytical methods.
• Assist in developing, optimizing, and troubleshooting experimental workflows and standard operating procedures.
• Compile, interpret, and present experimental findings using appropriate statistical and analytical methods.
• Maintain laboratory inventory, prepare reagents, monitor supplies, and coordinate purchasing of laboratory materials and equipment.

Requirements

• 3+ years of hands-on experience with human pluripotent stem cell culture (IPSC), differentiation, and maintenance.
• Experience in regenerative medicine, cell therapy, gene editing, or related therapeutic development fields.
• Experience working in a GMP-regulated biotech/biopharmaceutical environment.
• Extensive experience performing techniques such as flow cytometry, RT-qPCR, ddPCR, ELISA, and immunostaining methods.

Qualifications

Bachelor's or Master's degree in Biology, Cell Biology, Molecular Biology, Biotechnology, Regenerative Medicine, Genetics, or a related scientific discipline.

Schedule

40 hours per week (Thursday–Monday or Friday–Tuesday shift, including weekend work).

Pay

Salary: $70,000 – $100,000, commensurate with experience.

Benefits

• Medical, dental, and vision coverage.
• 401k retirement plan.
• Paid holidays.
• Paid time off (PTO).
• Sick leave as required by law.