Senior Research Assistant - Genomics and Quality Control

About the role

The Senior Research Assistant performs advanced laboratory and research activities in support of large-scale genomic sequencing projects and research initiatives at the Human Genome Sequencing Center (HGSC). This position independently executes complex laboratory procedures, maintains high-quality standards, assists with process optimization, and supports the production of high-quality genomic data for research and clinical sequencing programs.

Responsibilities

• Perform complex molecular biology laboratory procedures including nucleic acid extraction, quantification, quality assessment, library preparation, normalization, and sequencing workflow activities.
• Operate, troubleshoot, calibrate, and maintain laboratory instrumentation used in high-throughput genomic sequencing.
• Ensure accuracy, integrity, and traceability of biological samples throughout laboratory workflows.
• Review laboratory data for quality assurance and identify potential issues requiring corrective action.
• Assist in developing, validating, and implementing new laboratory methods, protocols, and process improvements to enhance efficiency, quality, and throughput.
• Maintain detailed laboratory records using Laboratory Information Management Systems (LIMS) and other electronic documentation systems.
• Train, mentor, and provide technical guidance to Research Assistants and new laboratory personnel.
• Monitor laboratory inventory, coordinate reagent preparation, and ensure adequate supplies to support uninterrupted production.
• Participate in quality assurance, proficiency testing, and continuous quality improvement activities.
• Assist with implementation and maintenance of Standard Operating Procedures (SOPs).
• Ensure compliance with institutional safety policies and applicable regulatory requirements, including CLIA, CAP, HIPAA, OSHA, and other quality standards as applicable.
• Collaborate with laboratory scientists, bioinformatics personnel, project managers, and operations staff to support project timelines and production goals.
• Participate in special projects, technology evaluations, and laboratory optimization initiatives.

Qualifications

Bachelor's degree in a Basic Science or related field and four years of relevant experience are required. Preferred qualifications include a Bachelor's or Master's degree in Biology, Molecular Biology, Genetics, Genomics, Biotechnology, Biochemistry, or a related scientific discipline, and experience working in a molecular biology, genomics, biotechnology, clinical laboratory, or high-throughput sequencing environment.

Candidates must be legally authorized to work in the United States at the time of application and throughout the duration of employment.