Jobs · Analyst · Oregon

Senior R&D Scientist – Novel Biologics Delivery

Lonza · Bend, OR · 1 mo ago
AnalystFull-time

About the role

The Senior R&D Scientist, Novel Biologics Delivery will join our Research & Development team in Bend, Oregon to lead the conceptualization, development, and experimental validation of innovative drug delivery platforms for proteins, peptides, and nucleic acids. This role bridges early-stage discovery and clinical translation.

Responsibilities

  • Translate analytical, developability, and mechanistic insights into innovative formulation and drug delivery platforms for injectable biologics, including mAbs, ADCs, and emerging modalities.
  • Apply translational science to design and assess novel drug delivery strategies.
  • Apply protein stability, aggregation, and interfacial behavior principles to guide formulation design for complex biologics.
  • Design, execute, and interpret advanced characterization and stability studies to guide development decisions.
  • Incorporate injectability, local tissue interactions, biological fate, and translational performance into formulation design for injectable biologics.
  • Develop and apply in vitro and ex vivo performance models to evaluate novel injectable formulation and delivery concepts.
  • Partner with cross-functional R&D teams to integrate analytical, formulation, process, and delivery perspectives into differentiated biologic drug product strategies.

Requirements

  • Ph.D. in pharmaceutical sciences, biochemistry, biophysics, chemical engineering, bioengineering, or a related discipline, 3–5 years of relevant industry experience.
  • Strong understanding of biologic developability, including protein stability, aggregation, degradation, interfacial behavior, and formulation–biologic interactions, DMPK and basic pharmacology.
  • Hands-on experience designing and interpreting formulation screening, stress, and stability studies for biologic drug products.
  • Expertise applying analytical characterization methods to connect molecular attributes with formulation performance and development decisions.
  • Working knowledge of injectable drug product development and sterile processing fundamentals.
  • Demonstrated ability to work effectively in cross-functional R&D teams.

Qualifications

  • Ph.D. in pharmaceutical sciences, biochemistry, biophysics, chemical engineering, bioengineering, or a related discipline, 3–5 years of relevant industry experience.
  • Strong understanding of biologic developability, including protein stability, aggregation, degradation, interfacial behavior, and formulation–biologic interactions, DMPK and basic pharmacology.
  • Hands-on experience designing and interpreting formulation screening, stress, and stability studies for biologic drug products.
  • Expertise applying analytical characterization methods to connect molecular attributes with formulation performance and development decisions.
  • Working knowledge of injectable drug product development and sterile processing fundamentals.
  • Demonstrated ability to work effectively in cross-functional R&D teams.

Skills

  • Strong understanding of biologic developability, including protein stability, aggregation, degradation, interfacial behavior, and formulation–biologic interactions, DMPK and basic pharmacology.
  • Expertise applying analytical characterization methods to connect molecular attributes with formulation performance and development decisions.
  • Working knowledge of injectable drug product development and sterile processing fundamentals.
  • Demonstrated ability to work effectively in cross-functional R&D teams.

Benefits

Compensation programs that recognize high performance. A variety of benefits dependent on role and location. The full list of our global benefits can be found here: https://www.lonza.com/careers/benefits.

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Commensurate with experience.

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