Senior Principal Scientist, Cardiovascular, Translational Development

About the role

Translational Development is part of the Global Research organization in BMS and leads late-stage clinical, pharmacological and translational research and development activities for the pipeline and supports late-stage portfolio for regulatory, translational development and life cycle management.

This group integrates laboratory science, clinical trial/biomarkers and asset development as well as disease research to maximize the potential of BMS current and future therapeutics.

Responsibilities

• Designs and implements program-specific development biomarker/translational plans
• Responsible for aiding in creation of clinical protocols, SAPs, SOWs, lab manual, and interfacing with CRO for execution of services, in conjunction with Biospecimen Operations and Procurement
• Determines appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicable
• Manages clinical biomarker data delivery and analysis and associated timelines by working with relevant internal functions and CROs
• Prepares and delivers internal and external translational/biomarker presentations
• Maintains timelines for biomarker data related publication through interaction with Medical Communications and Publication team as needed
• Keeps up-to-date on relevant scientific/technical literature in order to applying external knowledge to internal research programs as appropriate and acts as a subject-matter expert within the team to critically evaluate the literature regarding the asset and disease biology
• Works with TM laboratory scientists and academic TLs to address nonclinical translational questions as needed
• Participates/leads post-hoc biomarker analysis and publication efforts
• Supports regulatory submissions and regulatory interactions as needed
• Supports Diagnosis (PDx) biomarker assay development through collaboration with precision medicine group

Requirements

• PhD with 5–8+ years of translational medicine and clinical biomarker experience, including 5+ years supporting early- and/or late-stage clinical programs in biotech or pharma
• Recognized expertise in translational biomarkers in cardiovascular or related disease areas, with experience in drug development and clinical trial initiation, conduct, and completion
• Experience interacting with CROs and thought leaders to manage projects, timelines, and deliverables
• Demonstrated scientific and project leadership experience, including working in cross-functional teams, mentoring, and managing projects, with the ability to identify risks and implement contingency plans
• Experience mining and interpreting datasets in collaboration with bioinformaticians to understand mechanism of action, disease pathophysiology, or patient segmentation hypotheses
• Strong communication skills, including preparing and delivering presentations within the department, to governance and senior leadership, and externally as needed; recognizes and communicates cross-functional issues across the organization
• Able to support multiple projects in a fast-paced, collaborative environment, with strong organizational skills, attention to detail, and accurate record keeping

Qualifications & Experience

• Experience in cardiovascular or related disease areas, including but not limited to neurocardiac research
• Deep training and education in cardiovascular, or related disease areas
• Experience in drug development and clinical trial initiation, conduct, and completion
• Experience interacting with CROs and thought leaders to manage projects, timelines, and deliverables
• Experience mining and interpreting datasets in collaboration with bioinformaticians to understand mechanism of action, disease pathophysiology, or patient segmentation hypotheses
• Strong communication skills, including preparing and delivering presentations within the department, to governance and senior leadership, and externally as needed; recognizes and communicates cross-functional issues across the organization
• Able to support multiple projects in a fast-paced, collaborative environment, with strong organizational skills, attention to detail, and accurate record keeping

Skills

• Expertise in cardiovascular or related disease areas
• Experience in drug development and clinical trial initiation, conduct, and completion
• Experience interacting with CROs and thought leaders to manage projects, timelines, and deliverables
• Experience mining and interpreting datasets in collaboration with bioinformaticians to understand mechanism of action, disease pathophysiology, or patient segmentation hypotheses
• Strong communication skills, including preparing and delivering presentations within the department, to governance and senior leadership, and externally as needed
• Able to support multiple projects in a fast-paced, collaborative environment

Benefits

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Read more careers.bms.com/working-with-us.

Pay

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience.

Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location.

For more on benefits, please visit https://careers.bms.com/life-at-bms/.

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment.

Our benefits include:

• Health Coverage: Medical, pharmacy, dental, and vision care
• Wellbeing Support Programs: BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP)
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support

Schedule

Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs, and an annual Global Shutdown between Christmas and New Years Day.

Equal Opportunity Employer

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Read more careers.bms.com/working-with-us.