Senior Principal Research Scientist Engineering

About the role

The successful Process Engineering candidate will play a key technical team leader role in the R&D Process Engineering function. In addition to a strong background in fundamentals of chemical engineering, the ideal candidate will have demonstrated experience in the biologics, peptides, ADC development and genetic medicines as a strong technical team leader. The candidate must have demonstrated initiative in building and sustaining cross-functional collaborations. In addition to leading the technical team, the successful candidate is also expected to lead the identification and development of novel approaches and technologies to enhance process development efficiency and commercialization of novel modalities. The candidate must exhibit a collaborative behavior in proactively identifying process challenges on a wide range of pipeline and innovation projects, take a leadership role in a cross-functional team to deliver specific project needs, and take on a scientific leadership role in developing and implementing solutions.

Responsibilities

• Develop robust manufacturing processes, supporting assets including novel modalities through all phases of clinical development.
• Lead project teams towards process development and characterization of new synthetic and large molecule assets.
• Influence process development of toxins, cosmetic active ingredients and genetic medicines proactively.
• Lead scale-up of laboratory processes in the pilot plant.
• Set project strategies, define project responsibilities and timelines, and provide leadership in a matrixed team setting.
• Address challenging problems with biochemical reactions, separations, and/or isolations using expertise in reaction kinetics, transport phenomena, and mathematical modeling.
• Establish, communicate, and execute research plans.
• Exhibit a collaborative nature in identifying process challenges on a wide range of projects and communicate findings and recommendations effectively by multi-disciplinary interactions with organic chemists, analytical chemists, process development engineers, pilot plant engineers, drug product development scientists, program managers, and regulatory affairs specialists.
• Author and/or review technical documents summarizing process development efforts and contribute to regulatory filings.
• Strengthen scientific brand of Process Engineering while providing mentorship to direct reports and process engineering colleagues.

Requirements

• BS, MS, or PhD in Chemical/Bio Engineering or a related field and 18+ (BS), 16+ (MS), or 10+ (PhD) years of relevant biopharmaceuticals industrial experience.
• Job level will be commensurate with academic and/or industrial work experience.
• Candidates are expected to have a strong foundations in chemical engineering and the proven ability to demonstrate their skills in this field.
• The candidate is expected to demonstrate the ability to solve challenging technical problems and champion next generation of innovative technologies to achieve project goals around novel modalities.
• The candidate is required to be a strong team player and demonstrate scientific leadership, possessing effective oral and written communication skills for facilitating co-creation and leading cross-functional process development teams.

Qualifications

• BS, MS, or PhD in Chemical/Bio Engineering or a related field and 18+ (BS), 16+ (MS), or 10+ (PhD) years of relevant biopharmaceuticals industrial experience.
• Job level will be commensurate with academic and/or industrial work experience.
• Candidates are expected to have a strong foundations in chemical engineering and the proven ability to demonstrate their skills in this field.
• The candidate is expected to demonstrate the ability to solve challenging technical problems and champion next generation of innovative technologies to achieve project goals around novel modalities.
• The candidate is required to be a strong team player and demonstrate scientific leadership, possessing effective oral and written communication skills for facilitating co-creation and leading cross-functional process development teams.

Skills

• Strong background in fundamentals of chemical engineering.
• Demonstrated experience in the biologics, peptides, ADC development and genetic medicines.
• Initiative in building and sustaining cross-functional collaborations.
• Leadership in a matrixed team setting.
• Expertise in reaction kinetics, transport phenomena, and mathematical modeling.
• Effective oral and written communication skills.
• Collaborative behavior in proactively identifying process challenges.

Benefits

• Comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k).
• This job is eligible to participate in our short-term incentive programs.

Pay

$160,500 - $305,000 USD

Schedule

Full-time