Senior Molecular Technologist (Molecular Technologist III)

Description

The MaxCyte SeQure platform applies advanced genomics technologies for CRISPR gene editor target profiling to advance discovery, clinical development, and diagnostic solutions. This role engages with leaders in the field and supports a dynamic team with growth opportunities.

Job Responsibilities

• Perform complex molecular biology and NGS workflows, including sample preparation, nucleic acid processing, PCR, library preparation, library purification, quality control, sequencing, and other downstream processing activities.
• Execute testing in accordance with approved Standard Operating Procedures, study-specific instructions, development protocols.
• Operate and maintain automated liquid handling platforms, NGS sequencers, and other molecular laboratory equipment, including pipettes, thermocyclers, centrifuges, fluorometers, and fragment analysis instruments.
• Lead or troubleshoot assay failures, equipment malfunctions, automation errors, and unexpected quality control results.
• Support assay, instrument, and automation validation activities, including equipment qualification, technology transfer, verification, and implementation.
• Manage multiple concurrent workflows while maintaining accuracy, documentation quality, and turnaround time commitments.
• Lead or substantially contribute to investigations of deviations, nonconformances, incidents, assay failures, and other quality events, including root cause analysis and corrective and preventive actions.
• Author, review, revise, and implement SOPs, work instructions, forms, training materials, validation documents, and other controlled quality records.
• Support laboratory inventory management, reagent qualification, vendor evaluation, material forecasting, and implementation of alternative supplies or vendors.

Requirements

• Bachelor’s degree in clinical laboratory science, medical technology, molecular biology, biochemistry, genetics, chemical or biological sciences, or a related discipline.
• 5+ years of relevant molecular laboratory experience, including experience in a regulated, clinical, GLP, GMP, ISO or similarly controlled laboratory environment.
• Demonstrated experience with automated NGS workflows, laboratory documentation, and quality systems in a regulated environment.
• Demonstrated ability to independently troubleshoot complex molecular workflows and drive laboratory process improvements.
• Demonstrated ability to manage multiple laboratory activities while maintaining accuracy, quality, and turnaround-time commitments.
• Excellent written and verbal communication skills.

Preferred Qualifications

• Experience with CRISPR gene editing, off-target analysis, or cell and gene therapy applications.
• Experience with hybrid capture, targeted enrichment, high-throughput sequencing, or complex multiplexed library preparation.
• Experience with amplicon-based sequencing, targeted amplicon panel workflows, or similar targeted NGS applications, including library preparation, amplification, pooling, quality control, and sequencing.
• Master’s degree in molecular biology, genomics, bioinformatics, biotechnology, or a related scientific discipline or ASCP certification in molecular biology or another relevant laboratory certification.