Senior HR Business Partner

Position Summary

The Senior Human Resources Business Partner serves as a strategic leader and trusted advisor to senior leadership at Caris Life Sciences, driving enterprise-level people strategies that enable business growth, innovation, and organizational effectiveness. This role partners closely with executive stakeholders to design and implement workforce strategies, organizational structures, and leadership initiatives that support Caris' mission in precision medicine and oncology.

Job Responsibilities

• Serve as a strategic advisor to Vice President and senior executive leaders, aligning people strategy with business objectives and growth priorities.
• Lead organizational design initiatives, including structuring teams, optimizing spans and layers, and enabling scalable growth across functions.
• Develop and drive workforce planning strategies aligned with commercial expansion, clinical operations, and innovation priorities.
• Lead enterprise talent management processes, including succession planning, leadership development, and talent segmentation.
• Provide executive coaching to senior leaders on leadership effectiveness, organizational health, and team performance.
• Utilize HR analytics and business data to generate insights, forecast workforce needs, and influence executive decision-making.
• Lead complex management initiatives, including organizational transformations, restructures, and business scaling efforts.
• Partner with HR Centers of Excellence to design and implement enterprise HR solutions across compensation, talent acquisition, and development.
• Oversee and manage high-risk employee relations issues in partnership with Legal and Compliance to mitigate organizational risk.
• Drive culture and engagement strategies that reinforce a high-performance, mission-driven environment.
• Influence and shape HR strategy by providing feedback and direction to HR leadership and COE partners.
• Mentor and provide guidance to HRBP team members, helping to elevate overall HR capability.

Required Qualifications

• Bachelor’s degree in human resources, Business Administration, or related field.
• 5+ years of progressive Human Resources experience, including strategic HRBP experience.
• Demonstrated experience partnering with senior executives and leading organizational change initiatives.
• Proven ability to develop and implement workforce strategies aligned to business outcomes.
• Strong business acumen, with experience supporting commercial, clinical, or operational functions.
• Experience in organizational design, talent strategy, and leadership development.
• Exceptional communication, consulting, and influencing skills.
• Proficient in Microsoft Office Suite, specifically Word, Excel, Outlook, and general working knowledge of Internet for business use.

Preferred Qualifications

• Experience in life sciences, diagnostics, biotechnology, or healthcare industries.
• Experience supporting high-growth or rapidly scaling organizations.
• Master’s degree or MBA.
• HR certification (SHRM-SCP, SPHR).