Senior Distinguished Scientist for Transgenic Model and Technology

About the role

The Translational In Vivo Models (TIM) department within Sanofi's R&D is seeking an exceptional Senior Distinguished Scientist to lead our Transgenic Model & Technology (TMT) function globally. This strategic leadership role will drive innovation in genome engineering and genetically modified model development to accelerate drug discovery across all therapeutic divisions.

Key Responsibilities

• Lead and advance state-of-the-art genome engineering techniques and mouse genetics applications for in vivo model development supporting discovery and developmental research
• Apply personal expertise in transgenesis and CRISPR technology to devise and execute sophisticated experimental strategies for target validation, proof-of-concept, and efficacy studies
• Identify, evaluate, and implement new technologies and innovations in transgenesis, CRISPR/Cas systems, and emerging genome engineering platforms
• Serve as a strategic thinker and scientific advisor to research projects across therapeutic areas, providing expert guidance on in vivo and preclinical study design
• Champion the integration of AI and digital technologies to enhance model design, data analysis, and predictive capabilities in transgenic research
• Cover a broad scientific scope including immunology and immuno-inflammation, rare diseases, neuroscience, molecular and immune-oncology, and all areas of cell and molecular biology pertaining to immunology and immune-oncology

Strategic Planning & Cross-Functional Leadership

• Demonstrate strategic thinking and orientation in aligning transgenic capabilities with organizational research priorities and long-term scientific goals
• Lead and coordinate transversal teams and projects across multiple therapeutic divisions, sites, and external partners
• Collaborate closely with the Head of Transgenic Division, drug discovery program leaders, cluster heads, and department heads to provide strategic scientific advice
• Drive budget planning, forecasting, and financial management to optimize resource allocation and operational efficiency

Operational Excellence & Partnership Management

• Establish and maintain comprehensive project management frameworks ensuring full-service delivery from model design through study-ready animal production
• Build and manage strategic relationships with model providers, CROs, and academic partners for development and delivery of genetically modified models
• Negotiate and oversee license agreements and partnership contracts for model acquisition and technology access
• Implement quality standards and continuous improvement initiatives to maintain operational excellence

People Leadership & Development

• Supervise, mentor, and develop staff members to build a high-performing team at the forefront of transgenic science
• Participate in talent management decisions including hiring, promotions, performance evaluations, and organizational development
• Foster a culture of scientific excellence, innovation, collaboration, and continuous learning