Senior Director, Quantitative Pharmacology

Primary Responsibilities

• Key member of a product development team, contributing to the advancement of novel chemical entities bringing a quantitative perspective into strategic development to support continued investment
• Provide insight and leadership on pharmacokinetic aspects of clinical trials and programs and its application in development strategy
• Drive the implementation of pharmacometric principles and practices
• Development and execution of model-based analyses including translational PK/PD approaches, population pharmacokinetic models, exposure-response models, clinical trial design simulations, and quantitative systems pharmacology (QSP) modeling
• Provide pharmacometric support for programs through the worldwide marketing application filing including supportive registration documents and presentations
• Clear, timely communication and interpretation of study results to functional area experts and governance/senior management
• Contribute to assessment of internal and external opportunities
• Interface broadly with key functions including discovery sciences, preclinical development groups, toxicology, clinical operations, drug metabolism, regulatory affairs, and late-stage clinical research
• Mentoring and/or supervision of junior staff to perform above duties and support career development

Qualifications

• 5+ years of postdoctoral experience in quantitative pharmacology/pharmacometrics in the biotech and/or pharmaceutical industry
• Prior experience in the development and application of quantitative methods in drug development
• Strong background in population PK modeling, exposure response modeling and analysis, and developing statistical and mechanistic models for drug development
• Proven track record in clinical research and background in biomedical research
• Demonstrated record of scientific scholarship and achievement, willingness to work collaboratively across different therapeutic areas
• Strong interpersonal, writing and presentation skills, as well as the ability to function in a team environment are essential