Senior Director, Project Management Office (PMO)
Location: Valencia, CA (Hybrid role)
About the role
We are seeking a Senior Director, Project Management Office (PMO) to lead and evolve our enterprise PMO, ensuring the successful delivery of strategic, operational, regulatory, and transformational initiatives across a global organization. Reporting to the Vice President, Business Transformation & PMO, this role will serve as a trusted partner to executive leadership, driving portfolio governance, organizational prioritization, resource optimization, and project execution excellence. The ideal candidate brings a proven track record of PMO leadership, business transformation, and influencing outcomes within complex, matrixed environments.
Responsibilities
- Lead enterprise portfolio governance processes, including project prioritization, approval frameworks, portfolio reviews, and executive steering committees.
- Establish and continuously evolve PMO standards, methodologies, governance practices, and project delivery frameworks that drive consistency and accountability.
- Provide oversight of critical strategic initiatives, ensuring projects are executed effectively with strong risk management, stakeholder alignment, and predictable outcomes.
- Develop executive-level reporting, dashboards, KPIs, and portfolio analytics that enable data-driven decision-making and organizational transparency.
- Lead enterprise resource planning and capacity management processes to optimize prioritization, sequencing, and utilization of organizational resources.
- Partner with executive leaders to evaluate portfolio performance, identify risks and dependencies, and recommend strategic adjustments to maximize business value.
- Drive continuous improvement initiatives that enhance project delivery capabilities, governance maturity, and organizational effectiveness.
- Build, lead, and develop a high-performing PMO team while coaching project managers and business leaders on best practices in portfolio and project management.
- Support enterprise transformation initiatives and organizational change efforts that improve business performance and execution excellence.
Requirements
Education
- Required: Bachelor's degree in Business, Engineering, Life Sciences, Management, or a related field
- Preferred: MBA or other advanced degree
Certifications
- PMP
- PgMP
- PMI-ACP
- Prosci
- Other project, program, or change management certifications
Experience
- 12+ years of progressive experience in project management, program management, portfolio management, PMO leadership, or business transformation
- Proven experience leading enterprise PMO functions within complex, matrixed organizations
- Experience building and developing PMO teams and project management professionals
- Demonstrated success implementing governance frameworks, prioritization models, and delivery standards
- Experience leading cross-functional strategic initiatives and organizational transformation programs
- Strong executive communication and stakeholder management experience
Skills & Competencies
- Strategic thinker with strong business and financial acumen
- Expertise in project, program, and portfolio management methodologies
- Exceptional leadership, influencing, and relationship-building skills
- Strong decision-making abilities with a data-driven approach
- Experience managing enterprise resource planning and organizational capacity
- Ability to lead through ambiguity, complexity, and organizational change
- Continuous improvement mindset with a focus on execution excellence and measurable outcomes
- Proven ability to influence senior leaders and align stakeholders without direct authority
Nice to Have
- Experience implementing enterprise portfolio management tools such as OnePlan, Smartsheet, Jira, Planview, or similar platforms
- Experience within medical device, life sciences, healthcare, or other highly regulated industries
- Experience leading PMO transformations and enterprise change initiatives
- A minimum of 200Mb/sec download and 10Mb/sec upload speed internet connectivity
Benefits
- Medical, dental, and vision coverage
- Health Savings, Health Reimbursement, Flexible Spending/Dependent Care Accounts
- TeleHealth options
- 401k plan with company match
- Company paid life/AD&D insurance
- Additional supplemental life/AD&D coverage available
- Company paid Short/Long-Term Disability coverage (STD/LTD)
- STD/LTD Buy-ups available
- Accident/Hospital Indemnity coverage
- Legal/ID Theft Assistance
- PTO (or sick and vacation time), floating Diversity Day, & paid holidays
- Paid parental bonding leave
- Employee Assistance Program (24/7 mental health support hotline, 5 company paid counseling sessions and more)
- Robust Internal Career Growth opportunities
- Tuition reimbursement
- Hearing aid discount for employees and family
- Internal social recognition platform
*Plan rules/offerings dependent upon group Company/location.
Pay
This role's pay range is $175,000 – $240,000. This role is also bonus eligible.