Senior Director, Neuroscience Translational Pharmacology
for sections: About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule. Only include sections that have real specific content. We must not repeat job title as heading. Must not include Job ID/requisition numbers as headings; can fold minor metadata into short
or drop it. Must preserve all substantive information; do not invent or summarize away detail. Remove boilerplate etc. We need to parse the posting. Key sections: - Intro paragraph about BMS purpose, etc. That could be "About the role" or maybe "About the role" is generic. The instructions: use
for section headings (e.g. About the role, Responsibilities, Requirements, Qualifications, Skills, Benefits, Pay, Schedule). So we can create sections accordingly.
We need to decide what content goes where.
We have:
- Position Summary: description of role, location Cambridge, MA. That could be under "About the role".
- Position Responsibilities: list of duties (bulleted). Use - .
- Experience = Basic Qualifications: list of qualifications (education + years). That's "Requirements" maybe.
- Preferred Qualifications: list of preferred qualifications. Could be "Qualifications" or "Skills"? The instructions separate Requirements, Qualifications, Skills. We can map: Requirements = basic qualifications (must have). Qualifications = preferred qualifications? Skills = maybe the skills listed under preferred (communication, etc). But we need to avoid duplication.
Better: Use sections:
- About the role: includes purpose-driven culture, position summary, location.
- Responsibilities: the bullet list under Position Responsibilities.
- Requirements: basic qualifications (education + years + leadership experience).
- Qualifications: preferred qualifications (PhD etc). Could also include skills.
- Skills: maybe the communication skills etc. But we could combine.
- Benefits: the benefits paragraph.
- Pay: compensation overview with salary range.
- Schedule: not mentioned; we should not include Schedule section if no specific content.
We must not include sections with filler like "commensurate with experience". Not present.
We must not include boilerplate like EEO, legal, etc. Remove those.
We must preserve all substantive information. So we need to include details like: "The Neuroscience TRC is committed to the development of transformational therapeutics..." etc. That is substantive; should be included somewhere, maybe in About the role.
We need to ensure we don't lose any substantive info.
Let's extract substantive paragraphs:
Intro: "At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it."
Then description of Neuroscience TRC: "The Neuroscience TRC is committed to the development of transformational therapeutics for patients with neurodegenerative, neuromuscular and neuropsychiatric diseases. A network of internal and external partnerships across neurodegenerative and neuropsychiatric diseases and treatment modalities (small molecules, biologics and genetic medicines) supports our ambition to become leaders in neuroscience. Internal research focuses on causal human biology, matching therapeutic modality to molecular mechanism, and translational discovery enabling a rapid path to clinical proof-of-concept. Areas of interest include, but are not limited to, the identification of disease modifying and symptomatic therapies for neurodegenerative, neuropsychiatric and neuromuscular diseases; approaches to modulate protein clearance and reduce or eliminate toxic protein production; brain transporter technology and genetic medicines that when matched to underlying causal human biology may deliver a precision medicine portfolio with a high probability of translational success; AI/ML in target identification drug discovery; neuroimaging and fluid biomarkers to track disease progression and target engagement; novel blood brain-barrier technologies to enhance delivery of biotherapeutics and genetic medicines across the blood-brain barrier."
Then Position Summary: "The Neuroscience Thematic Research Center (Neuro TRC) leverages external collaborations and internal research to establish a portfolio targeting unmet needs in neurodegenerative, neuropsychiatric, neuroinflammatory and neuromuscular, diseases. The Senior Director, Neuroscience Discovery, in collaboration with other members of the Neuroscience TRC, be responsible for the design, conduct, and interpretation of translational pharmacology studies supporting the neuroscience discovery and early development pipeline, with particular emphasis on neurodegenerative and neuromuscular disease programs. This role serves as a key scientific and strategic partner across the Neuroscience TRC and broader BMS Research organization. This position is based in Cambridge, MA."
Then Position Responsibilities bullet list.
Then Experience = Basic Qualifications: list.
Then Preferred Qualifications: list.
Then "We hire for skills and capabilities, not just credentials – if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway."
Then Compensation Overview: salary range.
Then Benefits paragraph.
Then "How We Work" etc (work models) - could be considered part of About the role? Might be substantive but not required headings. Could be included in About the role as extra.
Then Supporting People With Disabilities etc - boilerplate? Might be considered EEO/legal; we should remove.
Candidate Rights etc - remove.
Data Protection etc - remove.
Job ID line at end: "R1606396 : Senior Director, Neuroscience Translational Pharmacology" - we should drop or fold into short p. Probably drop.
Thus we need to produce HTML with sections.
Let's craft:
About the role
At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.
The Neuroscience TRC is committed to the development of transformational therapeutics for patients with neurodegenerative, neuromuscular and neuropsychiatric diseases. A network of internal and external partnerships across neurodegenerative and neuropsychiatric diseases and treatment modalities (small molecules, biologics and genetic medicines) supports our ambition to become leaders in neuroscience. Internal research focuses on causal human biology, matching therapeutic modality to molecular mechanism, and translational discovery enabling a rapid path to clinical proof-of-concept. Areas of interest include, but are not limited to, the identification of disease modifying and symptomatic therapies for neurodegenerative, neuropsychiatric and neuromuscular diseases; approaches to modulate protein clearance and reduce or eliminate toxic protein production; brain transporter technology and genetic medicines that when matched to underlying causal human biology may deliver a precision medicine portfolio with a high probability of translational success; AI/ML in target identification drug discovery; neuroimaging and fluid biomarkers to track disease progression and target engagement; novel blood brain-barrier technologies to enhance delivery of biotherapeutics and genetic medicines across the blood-brain barrier.
The Neuroscience Thematic Research Center (Neuro TRC) leverages external collaborations and internal research to establish a portfolio targeting unmet needs in neurodegenerative, neuropsychiatric, neuroinflammatory and neuromuscular diseases. The Senior Director, Neuroscience Discovery, in collaboration with other members of the Neuroscience TRC, be responsible for the design, conduct, and interpretation of translational pharmacology studies supporting the neuroscience discovery and early development pipeline, with particular emphasis on neurodegenerative and neuromuscular disease programs. This role serves as a key scientific and strategic partner across the Neuroscience TRC and broader BMS Research organization. This position is based in Cambridge, MA.
Responsibilities
- Directly manage, mentor, and develop a team of scientists responsible for designing, executing, and interpreting in vivo and translational pharmacology studies across the neuroscience portfolio.
- Ensure scientific rigor, reproducibility, and regulatory-appropriate quality in study design, data interpretation, and reporting.
- Set team priorities, resource plans, and timelines aligned with program and portfolio needs.
- Work collaboratively to establish, maintain and integrate transgenic and other animal models to evaluate and select drug candidates for further investment.
- Contribute to Neuroscience portfolio governance within the Neuroscience TRC.
- Oversee the design and execution of pharmacology studies (efficacy, target engagement, PK/PD, biomarker) to support IND-enabling activities and entry into early clinical development.
- Partner with colleagues in Translational Discovery, Translational Medicine and early Clinical Development to ensure alignment between preclinical models and clinical biomarker/endpoint strategy.
- Play an active role in shaping research strategy across the neuroscience portfolio.
- Identify, recommend, and oversee relationships with academic collaborators and CRO partners; ensure quality, timelines, and scientific integrity of externally generated data.
- Represent the organization in interactions with external partners, guiding collaborative research activities.
Requirements
- Bachelor’s Degree and 15+ years of academic and/or industry experience
- Or Master’s Degree and 12+ years of academic and/or industry experience
- Or Ph.D. or equivalent advanced degree in the Life Sciences and 10+ years of academic and/or industry experience
- 8+ years of leadership experience
Qualifications
- PhD with 15+ years of experience in drug discovery research spanning small molecule, biotherapeutics and genetic medicines discovery
- Experience leading and supervising PhD, MS/MA and BS/BA scientists
- Experience creating and applying genetically engineered animal models of neurologic disease towards identification and characterization of novel therapeutics
- Experience leading drug discovery programs from ideation to delivery of a therapeutic candidate
- Expertise in quantitative analysis of neuropathological endpoints as applied to animal models of neurodegenerative disease
- Expertise in blood-brain-barrier delivery technologies spanning bi-specific antibodies and genetic medicines
- Experience leading and contributing to external collaborations and partnerships
- Experience participating on external diligence teams to identify opportunities for partnering and/or licensing
- Deep understanding of unmet need and clinical outcome measures used in studies focused on neurodegenerative disorders
- Excellent oral and written communication skills
- Ability to work both independently and as an integrated member of multidisciplinary drug development teams
We could also add a Skills section but we already have communication skills etc in Qualifications. Might be redundant. The instructions say we can have Skills section; but we prefer few substantive sections. We could move communication skills etc to Skills. But we already have them in Qualifications; maybe better to split: Qualifications = preferred qualifications (education/experience), Skills = communication etc. Let's do that.
Thus:
Qualifications (preferred qualifications about experience/education): PhD with 15+ years..., Experience leading..., Experience creating..., Experience leading..., Expertise in quantitative analysis..., Expertise in BBB..., Experience leading..., Experience participating..., Deep understanding...
Skills: Excellent oral and written communication skills; Ability to work both independently and as an integrated member...
We'll keep both.
Now Benefits:
Benefits
Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability). U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year. Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3
About the role
At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.
The Neuroscience TRC is committed to the development of transformational therapeutics for patients with neurodegenerative, neuromuscular and neuropsychiatric diseases. A network of internal and external partnerships across neurodegenerative and neuropsychiatric diseases and treatment modalities (small molecules, biologics and genetic medicines) supports our ambition to become leaders in neuroscience. Internal research focuses on causal human biology, matching therapeutic modality to molecular mechanism, and translational discovery enabling a rapid path to clinical proof-of-concept. Areas of interest include, but are not limited to, the identification of disease modifying and symptomatic therapies for neurodegenerative, neuropsychiatric and neuromuscular diseases; approaches to modulate protein clearance and reduce or eliminate toxic protein production; brain transporter technology and genetic medicines that when matched to underlying causal human biology may deliver a precision medicine portfolio with a high probability of translational success; AI/ML in target identification drug discovery; neuroimaging and fluid biomarkers to track disease progression and target engagement; novel blood brain-barrier technologies to enhance delivery of biotherapeutics and genetic medicines across the blood-brain barrier.
The Neuroscience Thematic Research Center (Neuro TRC) leverages external collaborations and internal research to establish a portfolio targeting unmet needs in neurodegenerative, neuropsychiatric, neuroinflammatory and neuromuscular diseases. The Senior Director, Neuroscience Discovery, in collaboration with other members of the Neuroscience TRC, be responsible for the design, conduct, and interpretation of translational pharmacology studies supporting the neuroscience discovery and early development pipeline, with particular emphasis on neurodegenerative and neuromuscular disease programs. This role serves as a key scientific and strategic partner across the Neuroscience TRC and broader BMS Research organization. This position is based in Cambridge, MA.
Responsibilities
- Directly manage, mentor, and develop a team of scientists responsible for designing, executing, and interpreting in vivo and translational pharmacology studies across the neuroscience portfolio.
- Ensure scientific rigor, reproducibility, and regulatory-appropriate quality in study design, data interpretation, and reporting.
- Set team priorities, resource plans, and timelines aligned with program and portfolio needs.
- Work collaboratively to establish, maintain and integrate transgenic and other animal models to evaluate and select drug candidates for further investment.
- Contribute to Neuroscience portfolio governance within the Neuroscience TRC.
- Oversee the design and execution of pharmacology studies (efficacy, target engagement, PK/PD, biomarker) to support IND-enabling activities and entry into early clinical development.
- Partner with colleagues in Translational Discovery, Translational Medicine and early Clinical Development to ensure alignment between preclinical models and clinical biomarker/endpoint strategy.
- Play an active role in shaping research strategy across the neuroscience portfolio.
- Identify, recommend, and oversee relationships with academic collaborators and CRO partners; ensure quality, timelines, and scientific integrity of externally generated data.
- Represent the organization in interactions with external partners, guiding collaborative research activities.
Requirements
- Bachelor’s Degree and 15+ years of academic and/or industry experience
- Or Master’s Degree and 12+ years of academic and/or industry experience
- Or Ph.D. or equivalent advanced degree in the Life Sciences and 10+ years of academic and/or industry experience
- 8+ years of leadership experience
Qualifications
- PhD with 15+ years of experience in drug discovery research spanning small molecule, biotherapeutics and genetic medicines discovery
- Experience leading and supervising PhD, MS/MA and BS/BA scientists
- Experience creating and applying genetically engineered animal models of neurologic disease towards identification and characterization of novel therapeutics
- Experience leading drug discovery programs from ideation to delivery of a therapeutic candidate
- Expertise in quantitative analysis of neuropathological endpoints as applied to animal models of neurodegenerative disease
- Expertise in blood-brain-barrier delivery technologies spanning bi-specific antibodies and genetic medicines
- Experience leading and contributing to external collaborations and partnerships
- Experience participating on external diligence teams to identify opportunities for partnering and/or licensing
- Deep understanding of unmet need and clinical outcome measures used in studies focused on neurodegenerative disorders
- Excellent oral and written communication skills
- Ability to work both independently and as an integrated member of multidisciplinary drug development teams
Benefits
Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans – including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability). U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year. Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3