Senior Director, Global Strategy and Program Management

What You’ll Do

• Lead the end-to-end strategy and execution for assigned oncology programs, with primary responsibility for CNS and Lung Cancer indications.
• Develop and maintain integrated program plans that align clinical development, regulatory strategy, evidence generation, commercialization planning, and lifecycle management activities.
• Serve as the strategic leader of the Program Development Team (PDT), fostering alignment across Clinical Development, Medical Affairs, Regulatory, Commercial, Market Access, and other key functions.
• Translate complex scientific, clinical, and business insights into actionable program strategies and clear organizational priorities.
• Persistently partner with functional leaders to ensure robust development plans, challenge assumptions, identify gaps, and drive execution against strategic objectives.
• Build organizational capability by guiding and influencing cross-functional team members, helping elevate strategic thinking and program leadership across the PDT.
• Define tumor-specific strategies, including indication prioritization, sequencing, lifecycle planning, and evidence generation approaches aligned with patient needs and market opportunity.
• Lead program governance activities, including preparation of recommendations and decision-making materials for Executive Leadership Team discussions and strategic reviews.
• Identify, assess, and proactively manage program risks, developing mitigation and contingency plans to support successful delivery.
• Serve as the central strategic voice and representative for assigned programs, ensuring consistent communication, alignment, and visibility across stakeholders.
• Develop and deliver executive-level presentations that communicate program strategy, progress, risks, opportunities, and key decisions.
• Drive continuous improvement of program leadership, governance, and strategic planning processes across the portfolio.

About You

• PhD, PharmD, MD, or equivalent advanced scientific degree in Life Sciences or a related discipline.
• 10+ years of experience within the biotechnology, pharmaceutical, or medical device industry, including significant (5+ years) oncology program leadership experience.
• Demonstrated experience leading complex global cross-functional development programs within a matrixed environment.
• Experience leading global oncology programs with responsibility across both US and international markets.
• Strong understanding of oncology drug, biologic, or medical device development, including regulatory pathways and commercialization considerations.
• Proven ability to integrate scientific, clinical, operational, and business perspectives into cohesive development strategies.
• Previous experience serving as a Program Lead, Global Program Leader (GPL), or equivalent leadership role within a Program Development Team (PDT) or comparable global development governance model.
• Experience presenting program strategies, recommendations, and decisions to senior executives and governance bodies.
• Ability to influence without direct authority and build alignment across diverse stakeholder groups.
• Willingness to travel approximately 30% domestically and internationally, including occasional weekend travel for congresses and internal meetings.
• Ability to work from the East Coast region of the United States, with preference for candidates located near Wayne, PA, Portsmouth, NH, Boston, MA, New York, or New Jersey.