Senior Director, Exploratory Biology

Key Responsibilities

• Establish internal capabilities to discover novel therapeutics for severe diseases in alignment with Vertex research strategy (validated targets to address causal human biology, creating predictive lab assays and identifying clinical biomarkers).
• Lead the team to identify disease indications and innovative approaches.
• Design and oversee proof-of-concept experiments to validate proposed treatment options.
• Build strong cross-functional collaborations across diverse scientific disciplines, including pharmacology, molecular and cell biology, chemistry, protein sciences, data and computational science, and engineering.
• Collaborate with internal stakeholders across commercial, clinical, regulatory, and other functions to build strategic plans.
• Partner with external academic and industry groups to advance research objectives.

Requirements

• Lead a team of 7+ highly experienced PhD level scientists, fostering a culture of scientific excellence and inclusion.
• Contribute to cross-site and cross-functional goals within Vertex.

Skills

• Expertise in molecular and cellular biology, pharmacology, physiology, and translational research.
• Strategic leadership and ability to integrate emerging technologies.
• Exceptional collaboration and stakeholder management skills.
• Track record of building high-performing teams and fostering innovation.

Knowledge

• MD/Ph.D. or Ph.D. in Biology or a related field.
• 12+ years of industry experience leading efforts in target identification, drug discovery, targeted delivery and translational research and an established track record of deliverables within an industrial research setting.
• Experience with multiple drug modalities (small molecules, nucleic acids, biologics, proteins, etc).
• Proven experience managing Ph.D.-level scientists and influencing at senior levels.
• Results-oriented leader with urgency, integrity, and professionalism.
• Ability to articulate vision and drive execution in a global, matrixed environment.
• Strong problem-solving, organizational, communication, and presentation skills.
• Desire to be part of a company transforming lives through innovation.

Pay

Pay Range: $217,000 - $325,400

Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law. At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more. Flex Designation: On-Site Designated Flex Eligibility Status. In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility. Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

Company Information: Vertex is a global biotechnology company that invests in scientific innovation. Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com