Senior Clinical Trial Manager (Sr. CTM) NX-5948-203

Senior Clinical Trial Manager (Sr CTM) You’ve run trials well — now run more of them, and help others do the same. You’ll manage a portfolio of trials or a full region, own vendor strategy end-to-end, and become the person other CTMs turn to when something’s stuck. Position Description This individual manages clinical regions and/or multiple trials simultaneously, with broad involvement in work central to Nurix’s strategic goals, and plays a key role in developing junior clinical operations staff. The Opportunity Own operational strategy across multiple clinical trials and/or a full geographic regionShape protocol strategy and provide senior input on study design and data collection approachLead vendor/CRO selection strategy and own contract negotiation leverage across trialsServe as the escalation point for vendor or site issues CTMs can’t resolve on their ownOwn program-level budget forecasting and proactively flag financial risk across the portfolioMentor and develop CTMs and CTAs, providing hands-on guidance and informal supervisionLead audit readiness strategy and serve as the point person across multiple trials during inspectionsRepresent Clinical Operations at the program or franchise level, and represent Nurix externally at professional eventsAnticipate risk across the trial portfolio and shape process or strategy to prevent issues before they surfaceLead cross-functional strategic initiatives rather than simply participating in them What You’ll Bring S./B.A. in biological sciences with 8-10+ years of relevant industry experienceAbility to travel as required for the program (25%)Deep working knowledge of FDA, EMA, ICH, and GCP regulations and guidelinesProven experience managing global trials or multi-region programsTrack record leading vendor/CRO relationships at a strategic, not just operational, levelExperience mentoring or developing junior CTMs/CTAsStrong executive presence and ability to influence without direct authorityComfortable operating with minimal oversight and setting direction for othersOutstanding organizational skills, able to manage a portfolio of trials simultaneouslyThrives in a fast-paced, small-company environment, adjusting priorities as needed Salary Range: $181,900 – $193.827 annually The posted range applies to roles based in the San Francisco Bay Area and reflects local market conditions. Where an offer lands within that range depends on the candidate’s relevant experience, technical expertise, and how their background aligns with the role’s requirements. Location: Onsite – Brisbane, CA Fit with Nurix Culture and Values Strong team orientation; highly collaborativeSolutions and results-oriented focusHands-on approach; resourceful and open to diverse points of view About Nurix Therapeutics Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.