Senior Associate Scientist, R&D Chemistry

About the role

We are currently seeking a synthetic organic chemist for the R&D (Research & Development) Chemistry group. In this position, they will play an important role in supporting Regeneron small molecule antibody-conjugate drug discovery capabilities, providing an important link with the company’s existing expertise in biologics and novel genetic medicines.

Responsibilities

• Enable in-house laboratory-based synthetic chemistry activities towards the discovery and generation of novel small-molecule payloads and linkers for antibody-drug conjugate therapeutics across research areas of oncology, metabolic disease/obesity, infectious diseases, immunology and inflammation, neuroscience, and ophthalmology.
• Work within the priorities set by the cross-functional teams and your supervisor. Ensure successful progression of the group’s technology and pipeline projects.
• Participate in departmental, cross-functional meetings to contribute expertise and to represent the goals of the R&D Chemistry group.
• Interact broadly and collaboratively with other Regeneron groups.

Requirements

• A M.Sc. in synthetic organic chemistry (or related), and familiarity with drug discovery processes and modern methods of synthetic organic and medicinal chemistry.
• A minimum of 5-7 years of industry drug discovery experience with small molecules is required.
• A firm understanding of modern organic synthesis strategies and techniques and the ability to work independently while deploying them in a fit-for-purpose efficient approach to biologically active targets of interest.
• Able to interpret spectroscopic data in the assignment/ confirmation of small molecule structures.
• Knowledge of the latest synthetic methods utilized in the antibody-conjugate linker generation is a plus.

Qualifications

• Cultural fit with the Regeneron chemistry and cross-functional teams is a priority.

Skills

• Small-molecule synthetic organic background and experience with the retrosynthetic analysis, synthetic route design, and hands-on execution of multistep synthetic protocols including compound isolation and characterization.

Benefits

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Pay

Salary Range (annually): $80,300.00 - $131,100.00

Schedule

Not specified