Senior Associate Scientist - Oncology Discovery

About the role

Working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department—from optimizing a production line to the latest breakthroughs in cell therapy. This is work that transforms the lives of patients and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams.

Responsibilities

• Designs and executes experiments based on cell and molecular biology protocols
• Analyzes and interprets experimental data
• Prepares and presents experimental results to project team leaders
• Works within established procedures to perform large-scale cell-based assays and screens
• Actively participates in troubleshooting to implement data-driven solutions to cell engineering challenges and optimize NGS library protocols to utilize new technologies
• Coordinates activities with other team members to achieve results

Requirements

• Bachelor’s Degree and 4+ years of academic and/or industry experience, or Master’s Degree and 2+ years of academic and/or industry experience

Qualifications

• Expertise across multiple gene editing platforms, including CRISPR/Cas9 and Perturb-seq, with direct experience in guide RNA design and verification of editing outcomes (e.g., genomic cleavage assays, flow cytometry-based reporters)
• Experience designing and executing NGS library preparation workflows for gene editing applications and CRISPR screens, with a focus on optimization for improved efficiency
• Skilled in both large-scale and single-cell CRISPR screen-enabling studies, including molecular cloning, plasmid design, cell engineering, lentiviral transduction, flow cytometry, western blot/JESS Simple Western, amplicon PCR, and large-format multilayer-flask tissue culture
• Experience supporting oncology drug discovery pipelines through design and execution of cell-based assays, with a focus on genetic-perturbation strategies to interrogate novel therapeutic targets
• Familiarity with lab automation platforms (a plus)
• Ability to effectively communicate scientific findings to cross-functional teams
• Proficiency using scientific data analysis programs including GraphPad Prism, FlowJo, Microsoft Excel and PowerPoint, Geneious, Benchling, and TapeStation Analysis Software

Benefits

• Health Coverage: Medical, pharmacy, dental, and vision care
• Wellbeing Support Programs: BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP)
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support
• Work-life Benefits:
  • Paid Time Off:
    • US Exempt Employees: Flexible time off (unlimited, with manager approval), 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico, or Rayzebio)
    • Phoenix, AZ, Puerto Rico, and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires (with manager approval), 11 national holidays, and 3 optional holidays

    Based on eligibility, additional time off may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs, and an annual Global Shutdown between Christmas and New Year’s Day.

All global full- and part-time employees actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

Pay

San Diego, CA – $100,480 - $121,756 (full-time employee basis). Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate accounts for required skills, job location, work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Schedule

This role follows BMS’s occupancy structure, which determines where work is conducted. The role is site-by-design, meaning it may be eligible for a hybrid work model with at least 50% onsite at the assigned facility. Onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive company culture.