Senior Associate Scientist, Obesity Muscle & Metabolism

About the role

The Obesity, Muscle and Metabolism group is seeking an enthusiastic Associate Scientist to advance our exciting discovery and translational programs focused on metabolic disease, skeletal muscle biology, and energy balance. The successful candidate will drive hands-on experimental work in cellular and in vivo systems, develop robust assays, and collaborate across biology, chemistry, pharmacology, and data science to generate decision-making data for pipeline programs. This is a lab-focused role suited for an experienced bench scientist with a strong foundation in metabolic biology.

Responsibilities

• Support or lead in vivo studies in rodent models of obesity, insulin resistance, and muscle dysfunction including compound dosing, tissue collection, and metabolic phenotyping
• Coverage of follow-up analysis of metabolic tissues from in vivo studies using qPCR, western blotting, immunohistochemistry and RNAScope
• Design, execute, and troubleshoot in vitro experiments in primary and immortalized cell models of adipocytes and myotubes including differentiation, stimulation, and compound testing
• Analyze and interpret data using appropriate statistical methods and clearly communicate findings in written reports and presentations
• Maintain meticulous electronic lab notebooks, SOPs, and assay documentation to ensure data integrity and reproducibility

Requirements

• In Vivo experience
• Bachelor's or Master's degree in Cell Biology, Physiology, Molecular Biology, Pharmacology, or related discipline
• Minimum of 3+ years of laboratory experience, preferably working with mouse models
• Experience designing and executing metabolic studies in rodent models of obesity including indirect calorimetry, glucose and insulin tolerance testing, assessing food intake and body composition
• Competence with data analysis and visualization tools such as Excel, Prism, R, or Python and sound understanding of experimental design and statistics
• Excellent presentation, time management, and collaborative skills

Preferred Qualifications

• Tissue culture, western blotting, ELISA and flow cytometry experience in various cell lines
• Histologic experience with metabolic tissues including liver, skeletal muscle, pancreas and brain